Endoscopic Tri-Modal Imaging increases the detection rate of colorectal adenomas compared to conventional colonoscopy.
ID
Bron
Aandoening
Colorectal, neoplasia, adenomas, Colonoscopy, Imaging, Detection, classification
Dutch: colon, neoplasie, adenomen, coloscopie, imaging, detectie
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Number of adenomas detected by ETMI versus conventional colonoscopy.
Achtergrond van het onderzoek
Colorectal adenomas are being missed by standard colonoscopy in about 22%. New imaging techniques try to reduce miss rates.
Endoscopic Tri-Modal Imaging (ETMI) incorporates (1) autofluorescence imaging and (2) high resolution endoscopy for detection, and (3) narrow band imaging for classification.
This study compares adenoma detection rates of ETMI with standard colonoscopy and evaluates the use of AFI and NBI for correct endoscopic diagnosis.
Doel van het onderzoek
Endoscopic Tri-Modal Imaging increases the detection rate of colorectal adenomas compared to conventional colonoscopy.
Onderzoeksproduct en/of interventie
ETMI tandem colonoscopy: High resolution endoscopy (HRE) followed by autofluorescence imaging (AFI).
Conventional colonoscopy: Standard resolution colonoscopy followed by standard resolution colonoscopy.
Algemeen / deelnemers
Department of Gastroenterology and Hepatology <br>
P.O. Box 22660
Evelien Dekker
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5664702
e.dekker@amc.uva.nl
Wetenschappers
Department of Gastroenterology and Hepatology <br>
P.O. Box 22660
Evelien Dekker
Meibergdreef 9
Amsterdam 1105 AZ
The Netherlands
+31 (0)20 5664702
e.dekker@amc.uva.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients (>18 years) undergoing colonoscopic surveillance because of:
a. history of adenomatous polyps.
b. history of CRC.
c. Hereditary Non-Polyposis Colorectal Cancer
d. family history of CRC/adenomas
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Poor bowel preparation;
2. Familial Adenomatous Polyposis, attenuated FAP, MYH associated polyposis or hyperplastic polyposis;
3. History of inflammatory bowel disease;
4. Presence of conditions precluding histological sampling of the colon (e.g. coagulation disorders, anticoagulant therapy).
Opzet
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1010 |
| NTR-old | NTR1039 |
| Ander register | : |
| ISRCTN | ISRCTN64206478 |