Light therapy for depression and diabetes

(1) male and female subjects 18 years or older; (2) having type 2 diabetes mellitus as judged by an expert panel based on HbA1c, diabetes medical history, use of glucose-lowering medication, and when deemed necessary additional tests (e.g. antibodies); and (3) having a major depressive episode according to DSM-IV criteria

1) a recent history of, or current, light therapy; (2) shift worker; (3) a recent change in antidepressant or blood-glucose lowering medication or therapy (e.g. psychotherapy); (4) use of oral glucocorticoids, melatonin, or cytostatics; (5) pregnancy; (6) psychosis, mania, (probable) dementia, severe drug or alcohol abuse, delirium, and severe acute suicidality; (7) a history of light-induced migraine or epilepsy, or severe side effects to light therapy in the past; (8) visual acuity <60%, diabetic retinopathy EURODIAB grades 3, 4 or 5 (severe non-proliferative or preproliferative retinopathy, photocoagulated retinopathy, proliferative retinopathy), senile macula degeneration; (9) a(nother) medical condition or recent medical event that potentially compromises the effects or safety of light therapy