Postoperative ileus is a well-known consequence of abdominal surgery which leads to prolonged hospital stay. Over the past years, the implementation of ERAS programs have lead to a reduction in postoperative hospital stay. The use of laxatives after…
ID
Bron
Verkorte titel
Aandoening
Colorectal pathology, laxatives, colorectal surgery, postoperative ileus
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Time to gastrointestinal recovery, defined as time to first flatus or first defecation.
Achtergrond van het onderzoek
Postoperative ileus is a well-known consequence of abdominal surgery which leads to prolonged hospital stay.
The objective of this trial is to compare time to gastrointestinal recovery after elective colorectal surgery between patients treated with a laxative versus patients treated with a placebo.
Doel van het onderzoek
Postoperative ileus is a well-known consequence of abdominal surgery which leads to prolonged hospital stay. Over the past years, the implementation of ERAS programs have lead to a reduction in postoperative hospital stay. The use of laxatives after colorectal surgery within these protocols is not yet evidence based.
The objective of this trial is to compare time to gastrointestinal recovery after elective colorectal surgery between patients treated with a laxative versus patients treated with a placebo.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
The laxatives being used in this trial are magnesiumoxide and bisacodyl. Patients will receive the laxative or the placebo for three days postoperatively, twice daily starting on the evening of surgery.
Algemeen / deelnemers
R.L.G.M. Blom
Atrium MC Heerlen afdeling chirurgie, Henri Dunantstraat 5
Heerlen 6401 CX
The Netherlands
+31 (0)45-5766666
r.blom@student.maastrichtuniversity.nl
Wetenschappers
R.L.G.M. Blom
Atrium MC Heerlen afdeling chirurgie, Henri Dunantstraat 5
Heerlen 6401 CX
The Netherlands
+31 (0)45-5766666
r.blom@student.maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients planned for elective colorectal surgery will be included regardless of age, underlying pathology or co-morbidity. Procedures to be performed include right hemicolectomy, transversectomy, left-hemicolectomy, sigmoid resection, low anterior resection, polypectomy, abdominoperineal resection, and laparoscopic right or left hemicolectomy.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Age <18 years;
2. Emergency procedures;
3. Contra-indications for the laxatives being used;
4. Lacking informed consent.
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1773 |
| NTR-old | NTR1883 |
| CCMO | NL28256.096.09 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON33165 |