1. Adherence to guidelines/protocols is unsatisfactory; 2. No regimen is superior in the proportion of patients with minimal or no impact of emesis on daily living as measured using the Functional Living Index-Emesis questionnaire.
ID
Bron
Verkorte titel
Aandoening
chemotherapy induced nausea and vomiting, adherence to guidelines, efficacy antiemetics, quality of life.
chemotherapie geinduceerde misselijkheid en braken, opvolgen behandelrichtlijnen, effectiviteit anti-emetica, kwaliteit van leven
Ondersteuning
Ziekenhuisapotheek Medisch Centrum Alkmaar
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. To make an inventory on the antiemetic policy in several peripheral hospitals;<br>
2. To make an inventory on the effectiveness of these antiemetic policies.
Achtergrond van het onderzoek
Nausea and vomiting are still two of the most serious side effects in chemotherapy treatment, even after the introduction of 5HT3 antagonists. The effectiveness of antiemetics used in the prevention of nausea and vomiting is not sufficient according to literature. Especially the prevention of delayed nausea and vomiting is difficult.
This study uses self reported sides effects including nausea and vomiting by means of a patient diary which also includes a quality of life assessment.
This outcomes research provides insight into the effectiveness of antiemetic policies in daily practice, in several peripheral hospitals.
Doel van het onderzoek
1. Adherence to guidelines/protocols is unsatisfactory;
2. No regimen is superior in the proportion of patients with minimal or no impact of emesis on daily living as measured using the Functional Living Index-Emesis questionnaire.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
This study uses self reported sides effects including nausea and vomiting by means of a patient diary which also includes a quality of life assessment.
Algemeen / deelnemers
P.O. Box 501
H.J. Doodeman
Alkmaar 1800 AM
The Netherlands
+31 72-5483591
h.j.doodeman@mca.nl
Wetenschappers
P.O. Box 501
H.J. Doodeman
Alkmaar 1800 AM
The Netherlands
+31 72-5483591
h.j.doodeman@mca.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Chemotherapy naive patients receiving chemotherapy.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Life expectancy less than three months;
2. Lack of basic proficiency in Dutch;
3. Age below 18;
4. Pregnancy;
5. Psychological illness.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL974 |
| NTR-old | NTR1001 |
| Ander register | : P05.0473L |
| ISRCTN | ISRCTN55375237 |