A higher (animal) protein and a higher essential amino acid intake (especially leucine) are associated with less decline in mid-thigh muscle cross-sectional area over a 5-year period.
ID
Bron
Aandoening
loss of muscle mass during aging;
verlies van spiermassa tijdens het proces van ouder worden
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
mid-thigh muscle cross-sectional area by computed tomography
Doel van het onderzoek
A higher (animal) protein and a higher essential amino acid intake (especially leucine) are associated with less decline in mid-thigh muscle cross-sectional area over a 5-year period.
Onderzoeksopzet
Year 1 (baseline): mid-thigh muscle cross-sectional area by CT
Year 6: mid-thigh muscle cross-sectional area by CT
Year 2: dietary intake with a food frequency questionnaire which reflects the intake of the previous year
Onderzoeksproduct en/of interventie
No intervention: this study is an prospective cohort study
Algemeen / deelnemers
Wetenschappers
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Data from the Health, Aging, and Body Composition (Health ABC) study were used. The Health ABC study is a prospective cohort study and investigates the association among body composition, weight related health conditions, and functional limitations in older adults. Between April 1997 and June 1998, 3075 well-functioning black and white men and women aged 70-79 were enrolled. Participants were recruited from a random sample of white Medicare-eligible residents and all of the black Medicare-eligible residents in the Pittsburgh, PA, and Memphis, TN, metropolitan areas. Subjects were eligible if they reported no difficulties in walking one-fourth of a mile, climbing up 10 steps, or performing basic activities of daily living; no history of active cancer in the 3 y prior to the study; planned to remain in the geographic area for ¡Ý3y; and were not enrolled in lifestyle intervention trials. All participants gave written informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Participants were excluded from the data-analyses if they had no good quality Computed Tomography (CT) data at year 1 (baseline) and year 6 of the HealthABC study and if they had no or no good quality dietary intake data (with a food frequency questionnaire)
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL6752 |
NTR-old | NTR6930 |
Ander register | NIA grant R01-AG028050 / National Institute on Aging (NIA) : N01-AG-6-2101; N01-AG-6-2103; N01-AG-6-2106; |