Dietary fibres and vinegar has been suggested to lower the postprandial blood glucose and insulin response and this may be explained by a delayed gastric emptying.
ID
Bron
Verkorte titel
Aandoening
1. Fibres;
2. acetic acid;
3. gastric emptying;
4. blood glucose;
5. satiety;
6. diabetes.
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Our hypothesis was that an intake of intact cereal kernels with vinegar would increase satiety, lower postprandial blood glucose and that this would be explained by a delay in gastric emptying rate.
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
Dietary fibres and vinegar has been suggested to lower the postprandial blood glucose and insulin response and this may be explained by a delayed gastric emptying.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Intact structural properties and vinegar has been suggested to lower the postprandial blood glucose and insulin response but the mechanism has not been clear. The aim was to study the effect of vinegar in combination with white wheat bread and bread containing different wheat fibre structures on the postprandial blood glucose response, satiety and the rate of gastric emptying in healthy subjects.
Methods: Fifteen healthy subjects were included and completed the blinded crossover trial. Gastric emptying rate (GER) was measured by standardized real time ultrasonography on the condition that fasting blood glucose was normal. Gastric emptying rate was calculated as the percentage change in the antral cross-sectional area 15 and 90 minutes after ingestion of white wheat, whole wheat kernel or wholemeal wheat bread with vinegar compared to white wheat bread as a reference. Blood glucose measurements were taken and satiety scores were estimated before and at 15, 30, 45, 60, 90 and 120 min after the start of the meal.
Algemeen / deelnemers
Joanna Hlebowicz
Malmö 205 02
Sweden
+46-40-331000
Joanna.Hlebowicz@skane.se
Wetenschappers
Joanna Hlebowicz
Malmö 205 02
Sweden
+46-40-331000
Joanna.Hlebowicz@skane.se
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Healthy subjects.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Symptoms or a prior history of gastrointestinal disease, abdominal surgery or diabetes mellitus.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL1083 |
NTR-old | NTR1116 |
Ander register | : |
ISRCTN | ISRCTN wordt niet meer aangevraagd |