A 3-month interactive cycling training is feasible and leads to improved executive functioning and physical fitness in early stage dementia patients. The association between physical activity and cognition is moderated by the presence of the ApoE4…
ID
Bron
Aandoening
Dementia, Alzheimer, Cognitive decline, Physical activity
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Executive functioning (set-shifting, response inhibition)
Achtergrond van het onderzoek
There is no cure for dementia. Non pharmacological interventions are needed. The aim of this study is to investigate the cognitive effects of an interactive cycling training in early stage dementia patients, compared to an aerobic stationary cycling training and an active control group.
Doel van het onderzoek
A 3-month interactive cycling training is feasible and leads to improved executive functioning and physical fitness in early stage dementia patients. The association between physical activity and cognition is moderated by the presence of the ApoE4 allele.
Onderzoeksopzet
Full assessments at pretest, after 12 weeks and at follow up (24 weeks). Short assessments after 6 weeks.
Onderzoeksproduct en/of interventie
Within the study, three interventions are provided: (1) Interactive aerobic stationary cycle training, (2) Aerobic stationary cycle training, (3) Non-aerobic stretching and toning exercises. Forty-five minute sessions were offered 3 times per week for a period of 12 weeks. The interactive cycling training is a dual-task training in which participants follow a route on a screen in front of the bike and conduct simple cognitive tasks.
Algemeen / deelnemers
Esther G.A. Karssemeijer
Reinier Postlaan 4 (route 925)
Nijmegen 6500 HB
The Netherlands
T (024) 36 16779
Esther.Karssemeijer@radboudumc.nl
Wetenschappers
Esther G.A. Karssemeijer
Reinier Postlaan 4 (route 925)
Nijmegen 6500 HB
The Netherlands
T (024) 36 16779
Esther.Karssemeijer@radboudumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Age > 60 years; diagnosis of dementia; Mini Mental State Examination score higher than 20; having insufficient physical activity according to the ACSM guideline for older adults, maximum of 30 minutes five days a week moderate intensity
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Wheelchair bound, use of dementia targeted nutritional supplements (e.g. Souvenaird) within the last three months, severe cardiovascular problems that limit physical activity, brain trauma, epilepsy, progressive or terminal disease, severe depression, history of alcoholism, severe visual problems, severe auditory problems, problems with the Dutch language and mental incompetence
Opzet
Deelname
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