It is hypothesized that both positive verbal suggestions regarding an inert substance and a positive imagery exercise result in a lower sensitivity to physical sensations (pain, itch, and fatigue) than neutral verbal suggestions and/or neutral…
ID
Bron
Aandoening
The study will be conducted in a sample of healthy volunteers.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The primary endpoint of this study is the effectiveness of the expectation manipulations in affecting sensitivity to pain, itch, and fatigue, i.e., the difference between the conditions in sensitivity to pain, itch, and fatigue (standardized sum score) after the expectation manipulations, as rated on visual analogue scales (VAS).
Achtergrond van het onderzoek
In the present project, the effects of two expectation manipulations (verbal suggestions regarding an inert substance and an imagery exercise) on self-reported sensitivity to physical sensations of pain, itch, and fatigue is examined. Additionally, the effects on physiological responses and the role of individual characteristics (e.g., optimism) will be explored.
Doel van het onderzoek
It is hypothesized that both positive verbal suggestions regarding an inert substance and a positive imagery exercise result in a lower sensitivity to physical sensations (pain, itch, and fatigue) than neutral verbal suggestions and/or neutral imagery.
Onderzoeksopzet
One timepoint. Participants take place in one experimental session during which the primary outcome measures are assessed once after the expectation manipulations.
Onderzoeksproduct en/of interventie
Expectation effects are induced by means of:
1. Positive versus neutral verbal suggestions on the effectiveness of a substance that is, unknown to the participants, inert;
2. A positive versus neutral imagery exercise in which participants focus on either their best possible health in the future or on a typical day.
Publiek
PO Box 9555
A.W.M. Evers
Leiden 2300 RB
The Netherlands
+31 (0)71 527 3627
a.evers@fsw.leidenuniv.nl
Wetenschappelijk
PO Box 9555
A.W.M. Evers
Leiden 2300 RB
The Netherlands
+31 (0)71 527 3627
a.evers@fsw.leidenuniv.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Age above 18 years;
2. Fluent in Dutch language.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Severe physical or psychological morbidity (e.g., heart and lung diseases, or DSM-IV psychiatric disorders) that would adversely affect participation;
2. Chronic pain, itch, or fatigue complaints, allergic rhinitis or asthma at present or in the past;
3. Use of beta-blockers or other medication that influence heart rate; use of pacemaker;
4. Inadequate health for physical exercise (Physical Activity Readiness Questionnaire);
5. Pregnancy.
6. Raynaud's phenomenon (18-jul-2014)
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL3509 |
| NTR-old | NTR3641 |
| CCMO | NL38953.091.12 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |
| OMON | NL-OMON37467 |