We hypothesise that one year compression therapy after DVT is equally effective as two years in the prevention of the post-thrombotic syndrome - in selected patients.
ID
Bron
Verkorte titel
Aandoening
post-thrombotic syndrome (posttrombotisch syndroom), compression therapy (compressietherapie), elastic stockings (elastische kousen), venous insufficiency (veneuze insufficientie), deep venous thrombosis (diep veneuze trombose)
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
- The incidence of post-thrombotic syndrome in the second year of compression therapy.
Achtergrond van het onderzoek
Prospective single-blind study to the optimal duration of ambulant compression therapy (ACT) after deep venous thrombosis as prevention of the post-thrombotic syndrome. After one year of ACT patients are randomized to either continuing ACT for a following year or stopping therapy. At inclusion, a blind duplex ultrasound is performed to evaluate its predictive value in PTS, as well as evaluation of baseline characteristics and laboratory findings. Quality of Life assessment is done at inclusion and after one year follow-up.
Doel van het onderzoek
We hypothesise that one year compression therapy after DVT is equally effective as two years in the prevention of the post-thrombotic syndrome - in selected patients.
Onderzoeksopzet
T=0 randomization, duplex ultrasound, QoL
T=3 follow-up PTS (phone interview)
T=6 follow-up PTS (outpatient clinic)
T=12 follow-up PTS (outpatient clinic), QoL
Onderzoeksproduct en/of interventie
At inclusion, patients will be randomized in two groups; one receiving a following year of compression therapy, one without.
Publiek
G.C. Mol
Bosboomstraat 1
Utrecht 3582 KE
The Netherlands
+31 (0)30 2566566
GMol@diakonessenhuis.nl
Wetenschappelijk
G.C. Mol
Bosboomstraat 1
Utrecht 3582 KE
The Netherlands
+31 (0)30 2566566
GMol@diakonessenhuis.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. All patients with deep venous thrombosis who received one year of compression therapy.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Recurrent ipsilateral DVT
2. Contra indication for (stopping) compression therapy
Opzet
Deelname
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