The current study aims to investigate the reliability of the AUDIT questionnaire in comparison to the PEth marker value in the general ED population. Thereby we would like to explore if there are advantages of using an objectified direct alcohol…
ID
Bron
Verkorte titel
Aandoening
Hazardous Alcohol Use
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Primary Objective:
- Determine the reliability of the AUDIT questionnaire compared to the PEth marker in the general ED population.
Achtergrond van het onderzoek
Almost 10% of the Dutch population drinks excessively. The range of possible harmful effects of hazardous alcohol use is widespread and associated with extensive impact on our healthcare system. The Emergency Department (ED) is a location for the early identification of problematic alcohol users. Up to 15% of all attendances in the ED is alcohol related. Identification of risky drinkers is important because this provides possibilities for future intervention/prevention strategies. Previous studies identified risky drinkers mostly by questionnaire such as the Alcohol Use and Identification Test (AUDIT), which are subject to the risk of response bias. Phosphatidylethanol (PEth) is a direct blood marker of chronic alcohol use/abuse and can be used to objectively identify risky drinkers. Literature shows the advantages of this PEth marker compared to the AUDIT questionnaire in different populations outside the ED. To this moment, no studies have investigated this marker within the general ED population.
The primary aim of the current study is to investigate the reliability of the AUDIT questionnaire when compared to the PEth marker value for the screening of hazardous alcohol use in the general ED population. Secondary aim is to investigate the correlation between the PEth marker value and the scores on the AUDIT, two-week period Timeline Followback including a 24-hour questionnaire, in the general ED population.
Doel van het onderzoek
The current study aims to investigate the reliability of the AUDIT questionnaire in comparison to the PEth marker value in the general ED population. Thereby we would like to explore if there are advantages of using an objectified direct alcohol marker for screening for problematic alcohol use in the general ED population.
Onderzoeksopzet
T1. During presentation at the Emergency Department
Onderzoeksproduct en/of interventie
Not applicable
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
The population is the general adult ED population from who blood will be drawn.
Inclusion criteria
In order to be eligible to participate in this study, a patients must meet all of the following criteria:
- Present to the ED of the Erasmus Medical Center in Rotterdam.
AND
- Their attending physician decided that blood has to be drawn for medical reasons (independently of this study)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Age < 18.
- Language barrier.
- Inclusion only if patients have a good command of Dutch language.
- No informed consent.
- Previous participation in this study.
- Intoxication with alcohol and/or other drugs/substances.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
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In overige registers
Register | ID |
---|---|
NTR-new | NL7590 |
Ander register | Medisch Ethische Toetsings Commissie : MEC-2017-564 |