To determine the effect of an early MRSA detection strategy on nosocomial MRSA infections in a cohort of surgical patients at a large teaching hospital.
ID
Bron
Verkorte titel
Aandoening
MRSA control in surgery.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Number of patients with nosocomial MRSA infection acquired in surgery, expressed as incidence per 1000 patient-days
Achtergrond van het onderzoek
Background:
Carriage of methicillin-resistant Staphylococcus aureus (MRSA) places patients at risk for MRSA infection. Experts and politicians have repeatedly called for widespread admission screening to reduce nosocomial MRSA infection.
Objectives:
To determine the effect of an early MRSA detection strategy on nosocomial MRSA infections in a cohort of 21’754 surgical patients at a large teaching hospital.
Methods:
We carried out a prospective, interventional cohort study using a cross-over design to compare two different MRSA control strategies (rapid screening plus standard control versus standard control only). Twelve surgical wards were assigned to 2 study groups and enrolled according to a pre-specified agenda, encompassing 4 study phases. Patients admitted for >24 h were screened upon admission by quick, multiplex PCR. MRSA infections acquired in surgery were the primary outcome measure.
Doel van het onderzoek
To determine the effect of an early MRSA detection strategy on nosocomial MRSA infections in a cohort of surgical patients at a large teaching hospital.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Rapid MRSA screening.
Publiek
Infection Control Program
Stephan Harbarth
24, rue Micheli-du-Crest
Geneva 1211
Switzerland
+41 22 372 3357
stephan.harbarth@hcuge.ch
Wetenschappelijk
Infection Control Program
Stephan Harbarth
24, rue Micheli-du-Crest
Geneva 1211
Switzerland
+41 22 372 3357
stephan.harbarth@hcuge.ch
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
All patients admitted to the surgical department for >24 hours.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Ambulatory surgery.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1012 |
| NTR-old | NTR1041 |
| Ander register | : |
| ISRCTN | ISRCTN06603006 |