Epidral analgesia has superior pain management outcomes. On the other hand we hypothize EA requires more aggressive hemodynamic support, leading to higher risk of postoperative complications.
ID
Bron
Aandoening
Epidural analgesia (EA) is the current golden standard for perioperative pain management in most abdominal surgery. However, as demonstrated by the variety of reported use of EA (ranging approximately from 10%-84%), the golden standard in patients undergoing pancreatectomy has yet to be determined.The reported benefits from EA in abdominal surgery might not apply to patients undergoing pancreatectomy.
In contrast to the beneficial reported effect on postoperative complications of EA in abdominal surgery, recent studies described an adverse effect of EA on postoperative complications, Intensive Care Unit (ICU) admissions and length of hospital stay (LOS). Although some studies reported a (marginally) better postoperative pain control in patient with EA compared to other analgesic management options, detailed reports on pain outcomes after pancreatectomy are sparse.
The aim of this study is to evaluate the current practice of analgesic management and outcomes in patients undergoing pancreatectomy in our tertiary referral center.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Mean NRS on first ten postoperative days
Achtergrond van het onderzoek
Epidural analgesia (EA) is the current golden standard for perioperative pain management in most abdominal surgery. However, as demonstrated by the variety of reported use of EA (ranging approximately from 10%-84%), the golden standard in patients undergoing pancreatectomy has yet to be determined. The reported benefits from EA in abdominal surgery might not apply to patients undergoing pancreatectomy.
In contrast to the beneficial reported effect on postoperative complications of EA in abdominal surgery, recent studies described an adverse effect of EA on postoperative complications, Intensive Care Unit (ICU) admissions and length of hospital stay (LOS). Although some studies reported a (marginally) better postoperative pain control in patient with EA compared to other analgesic management options, detailed reports on pain outcomes after pancreatectomy are sparse.
The aim of this study is to evaluate the current practice of analgesic management and outcomes in patients undergoing pancreatectomy in our tertiary referral center.
Doel van het onderzoek
Epidral analgesia has superior pain management outcomes. On the other hand we hypothize EA requires more aggressive hemodynamic support, leading to higher risk of postoperative complications.
Onderzoeksopzet
- Data collection start dec 2017
- Data analyses start feb 2018
- First draft apr 2018
- Submission jun 2018
Onderzoeksproduct en/of interventie
Observational study in patient with epidural versus non-epidural analgesia
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
All consecutive patients undergoing elective or emergency (open procedure) pancreatectomy for (suspected) malignant disease
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Laparoscopic procedure.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6701 |
| NTR-old | NTR6871 |
| Ander register | Commissie Medische Ethiek, Leids Universitair Medische Centrum : G12.059 |