1. The training program will result in improved stability of walking; 2. The training program will result in improved rate of bone turnover (indicative of improvement in bone mass).
ID
Bron
Aandoening
Ageing
Inactivity
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. Stability of unperturbed walking (Local dynamic stability and variability of walking);<br>
2. Stability of perturbed walking (size of deflection from normal walking pattern and speed of return to normal walking pattern);<br>
3. Indicators of bone turnover (markers of bonedegeneration: CTx; markers of bone synthesis: osteocalcine en P1NP).
Achtergrond van het onderzoek
Physical inactivity becomes more prominent as people age. Physical inactivity and ageing results in decreasing bone and muscle mass and decreased muscle functioning, which results in increasing difficulty in performing daily activities. Another problem with increasing age is the increased incidence of falls. Falls often lead to decreased functioning, reduced participation, early placement in nursing homes and premature death.
The aim of this study is to investigate if a 16 weeks training program with combined functional gait and strength training results in improved stability of walking and improved bone turnover.
Doel van het onderzoek
1. The training program will result in improved stability of walking;
2. The training program will result in improved rate of bone turnover (indicative of improvement in bone mass).
Onderzoeksopzet
1. Baseline;
2. Baseline + 16 weeks (post training);
3. Baseline + 24 weeks (follow up).
Onderzoeksproduct en/of interventie
The intervention consists of 16 weeks of twice weekly combined gait- and strength training in groups of maximally 10 subjects. Each training sessions has a duration of 1 hour. The training will be executed in a gym under supervision of an instructor.
The training will consist of exercises that challenges balance during standing and walking (e.g. standing or walking on a compliant surface) and of exercises that improves muscle function of the lower extremities using body weight and, if possible, small external weights. The difficulty of the exercises will be adapted to individual capabilities.
The control group will not receive a training or other intervention during the trial. The control group will receive a delayed intervention after the final measurement.
Publiek
Marcel Toebes
Amsterdam 1081 BT
The Netherlands
+31 (0)20 5982955
m.toebes@fbw.vu.nl
Wetenschappelijk
Marcel Toebes
Amsterdam 1081 BT
The Netherlands
+31 (0)20 5982955
m.toebes@fbw.vu.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. 65-75 years;
2. Male or femaie;
3. Community dwelling;
4. No active sports participation for at least 12 months.
Subjects are recruited via advertisementS in local newspapers.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Vacscular-, neurological- or musculosceletal diseases that would interfere with the ability to walk, the use of walking aids or contra-indications for strength testing.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL2319 |
NTR-old | NTR2425 |
Ander register | METC VUmc : 2010/67 |
ISRCTN | ISRCTN wordt niet meer aangevraagd. |