Continuous infusion compared with intermittent flushing to minimize loss of function of iv in neonates.

Comparison of loss of function between continuous iv and intermittend flushing in neonates who need an iv for drug administration.

We expect no difference in loss of function time between continuous iv and intermittend flushing.

Other studies only compared intermittend flushing with NaCl/Heparine versus continuous glucose 10%. Seen the risk for flebitis using concentrated glucose solution we hypothesise a better outcome using glucose 5%. Because recent study shows flushing with heparin is as effective as flushing with NaCl 0,9% we use NaCl 0,9%.

An iv that will be flushed intermittendly will not loose his function easier than a continuous iv.

1. No more need for iv drug administration;

2. 72 hours.

1. Continuous iv glucose 5% 2ml/h;

2. Continuous iv glucose 5% 1ml/h;

3. Iv flushed 4 times a day with 2 ml NaCl 0,9%.