Purpose of this study is to investigate if methionine PET scanning [combined with MRI scanning] has added value in the follow-up of intracranial meningioma compared to MRI scanning alone.
ID
Bron
Verkorte titel
Aandoening
meningioma, follow-up, methionine PET
Ondersteuning
Healthy Aging Pilot-subsidy
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The difference between the MRI-only and MRI/methionine PET report
Achtergrond van het onderzoek
The aim of this study is to investigate whether MET-PET in combination with MRI has added value over MRI alone in the follow-up of patients with meningiomas in difficult intracranial localizations after SRT.We plan to include a cohort of 35 adult patients who have been treated for an intracranial meningioma with SRT and had their radiotherapy field (partially) planned on MET-PET (irrespective of preceding neurosurgical resection of the tumour). The included patients get repeated MET-PET in addition to the 1-year regular follow-up MRI-scan (care as usual). Finally, we evaluate the differences in findings (progression or not) between follow-up MRI + MET-PET versus follow-up MRI alone.
Doel van het onderzoek
Purpose of this study is to investigate if methionine PET scanning [combined with MRI scanning] has added value in the follow-up of intracranial meningioma compared to MRI scanning alone.
Onderzoeksopzet
Participants will have a methionine PET scan in adjunct to their regular once-a-year MRI scan
Onderzoeksproduct en/of interventie
Participants of this study will undergo a methionine PET scan in addition to their regular follow-up MRI-cerebrum
Publiek
J.R. Jeltema
Hanzeplein 1 - PO Box 30.001
Groningen 9700 RB
The Netherlands
+31-50-3612837l
j.r.jeltema@umcg.nl
Wetenschappelijk
J.R. Jeltema
Hanzeplein 1 - PO Box 30.001
Groningen 9700 RB
The Netherlands
+31-50-3612837l
j.r.jeltema@umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- age above 18 years
- profound understanding of the dutch language
- treatment with SRT for an intracranial meningioma with a pre-treatment MET-PET for radiation field planning purposes
-Able to give written informed consent
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Adverse reaction during previous MET-PET scanning
- Pregnancy
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL6968 |
NTR-old | NTR7156 |
CCMO | NL63750.042.17 |
OMON | NL-OMON44234 |