Administration of probiotics to pregnant women from an atopic family and subsequently to their high-risk newborns results in prevention of the incidence of or in a decrease of the severity of atopic disease during infancy.
ID
Bron
Verkorte titel
Aandoening
A randomised double-blind intervention study in pregnant mothers from atopic families and in their newborns.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Incidence and severity of atopic disease at the age of 2 years.
Achtergrond van het onderzoek
Inclusion of pregnant mothers from atopic families has ended. Around January first 2006 all children are born. Results on cord blood analysis are expected in spring of 2006. Clinicial data at the age of 3 months are expected just before the summer of 2006.
Doel van het onderzoek
Administration of probiotics to pregnant women from an atopic family and subsequently to their high-risk newborns results in prevention of the incidence of or in a decrease of the severity of atopic disease during infancy.
Onderzoeksproduct en/of interventie
A combination of probiotics (Lact.Lactis, B.Bifidum, B.Infantum), each 1000 milion daily, added to the the formula used.
Publiek
Wilhelmina Children's Hospital,
P.O. Box 85090
M.O. Hoekstra
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504001
m.o.hoekstra@umcutrecht.nl
Wetenschappelijk
Wilhelmina Children's Hospital,
P.O. Box 85090
M.O. Hoekstra
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504001
m.o.hoekstra@umcutrecht.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Pregnant mothers were included if either they themselves or their husband plus a sibling suffered from present or past atopic disease.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Maternal use of immunomodulatory drugs during pregnancy;
2. The use of probiotics.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL285 |
| NTR-old | NTR323 |
| Ander register | : N/A |
| ISRCTN | ISRCTN52995544 |