We did not have a hypothesis because this is a new disease and the approach of the study is more explorative.
ID
Bron
Verkorte titel
Aandoening
COVID-19
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Exploratory research into possible variables in CPET and pulmonary function tests that are abnormal after suffering from COVID-19. Therefore it is not possible to define 1 primary outcome measure.
Achtergrond van het onderzoek
Background: There is a lack of knowledge about the recovery and possible detrimental long-term effects after COVID-19. Current clinical practice shows that some patients experience persistent symptoms after suffering from COVID-19. With this study we want to get more insight in the causes and mechanisms of these symptoms using pulmonary function tests and a cardiopulmonary exercise test (CPET).
Question: What are the pulmonary and fitness characteristics of patients who have persistent symptoms of dyspnea and / or reduced exercise capacity after suffering from COVID-19?
Design: Prospective observational study.
Method: Patients who are approached for participation in this study: (1) have had COVID-19, (2) have persistent symptoms of dyspnea (in rest and/or during exercise) and (3) are referred to the department of pulmonology or sports medicine in the OLVG hospital. The clinical work-up is up to the treating doctor. For this study we collect data of pulmonary function tests (including diffusion capacity), cardiopulmonary exercise tests and chest X-rays. Follow-up is planned about 9-12 months after the first visit.
Doel van het onderzoek
We did not have a hypothesis because this is a new disease and the approach of the study is more explorative.
Onderzoeksopzet
baseline and follow-up after 9-12 months
Onderzoeksproduct en/of interventie
none
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Suffered from COVID-19 based on clinical criteria (fever, dyspnea, coughing, loss of smell and/or loss of taste) in March 2020 or later and currently have symptoms of dyspnea (in rest and/or during exercise) and/or reduced exercise capacity.
2. Age: 16 years or older.
3. Normally doing sports at least once a week.
4. Is able to perform a CPET.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Another diagnosis is regarded as the cause of the symptoms.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL9093 |
| Ander register | Wetenschapsbureau ACWO of OLVG Hospital : WO 20.148 |