A higher (animal) protein and a higher essential amino acid intake (especially leucine) are associated with less decline in mid-thigh muscle cross-sectional area over a 5-year period.
ID
Bron
Aandoening
loss of muscle mass during aging;
verlies van spiermassa tijdens het proces van ouder worden
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
mid-thigh muscle cross-sectional area by computed tomography
Doel van het onderzoek
A higher (animal) protein and a higher essential amino acid intake (especially leucine) are associated with less decline in mid-thigh muscle cross-sectional area over a 5-year period.
Onderzoeksopzet
Year 1 (baseline): mid-thigh muscle cross-sectional area by CT
Year 6: mid-thigh muscle cross-sectional area by CT
Year 2: dietary intake with a food frequency questionnaire which reflects the intake of the previous year
Onderzoeksproduct en/of interventie
No intervention: this study is an prospective cohort study
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Data from the Health, Aging, and Body Composition (Health ABC) study were used. The Health ABC study is a prospective cohort study and investigates the association among body composition, weight related health conditions, and functional limitations in older adults. Between April 1997 and June 1998, 3075 well-functioning black and white men and women aged 70-79 were enrolled. Participants were recruited from a random sample of white Medicare-eligible residents and all of the black Medicare-eligible residents in the Pittsburgh, PA, and Memphis, TN, metropolitan areas. Subjects were eligible if they reported no difficulties in walking one-fourth of a mile, climbing up 10 steps, or performing basic activities of daily living; no history of active cancer in the 3 y prior to the study; planned to remain in the geographic area for ¡Ý3y; and were not enrolled in lifestyle intervention trials. All participants gave written informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Participants were excluded from the data-analyses if they had no good quality Computed Tomography (CT) data at year 1 (baseline) and year 6 of the HealthABC study and if they had no or no good quality dietary intake data (with a food frequency questionnaire)
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL6752 |
NTR-old | NTR6930 |
Ander register | NIA grant R01-AG028050 / National Institute on Aging (NIA) : N01-AG-6-2101; N01-AG-6-2103; N01-AG-6-2106; |