This study aims to investigate the value and feasibility of a disposable TEE to monitor both fluid responsiveness and global contractile function of both left and right ventricles in high risk surgical patients, including both intraoperative…
ID
Bron
Verkorte titel
Aandoening
major surgery with large fluid shifts, Hemodynamic Monitoring, fluid responsiveness, contractile function of both left and right ventricles
Ondersteuning
Laarbeeklaan 101
1090 Jette
Belgium
Laarbeeklaan 101
1090 Jette
Belgium
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Diagnosis of fluid responsiveness and ventricular failure at the hereunder described timepoints.
Achtergrond van het onderzoek
In a comparative prospective study a disposable TEE will be used to compare diagnosis of fluid responsiveness and ventricular failure in high risk surgical patients. The comparative monitoring will be a non-invasive haemodynamic monitor, providing beat-to-beat cardiac output and blood pressure variability (Nexfin).
Doel van het onderzoek
This study aims to investigate the value and feasibility of a disposable TEE to monitor both fluid responsiveness and global contractile function of both left and right ventricles in high risk surgical patients, including both intraoperative management and postoperative follow up in a high dependency unit of a university hospital, against the information obtained from a non-invasive hemodynamic monitoring tool.
Onderzoeksopzet
After induction of anesthesia, at each period of hemodynamic instability, before extubation, and in the postoperative phase on arrival in the high-dependency unit and every 4 hrs thereafter. Whenever hemodynamic instability occurs, an evaluation in addition will be performed.
Onderzoeksproduct en/of interventie
Insertion of an echoprobe in the oesophagus via nose. The tool is used solely for hemodynamic monitoring. The final diagnosis is performed by the attending anesthetist.
Publiek
Veerle Mossevelde, van
Brussels 1090
The Netherlands
+32 (0)2 4763134
veerle.vanmossevelde@uzbrussel.be
Wetenschappelijk
Veerle Mossevelde, van
Brussels 1090
The Netherlands
+32 (0)2 4763134
veerle.vanmossevelde@uzbrussel.be
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
All patients (aged between 18 and 75 y) are scheduled for high-risk abdominal, gynecological, vascular or orthopedic surgery.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Excluded are those patients undergoing upper gastro-intestinal surgery with an impossibility to perform a TEE investigation. Also not enrolled are patients suffering from coagulopathy, or inability to insert a transesophageal probe for whatever medical reason.
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL3176 |
NTR-old | NTR3320 |
Ander register | MEC UZ Brussel : 2011/214 |
ISRCTN | ISRCTN wordt niet meer aangevraagd. |