The reported incidence of dysphagia in multiple sclerosis (MS) varies between 33% and 90% and is higher in more disabled patients. Dysphagia is associated with an increased risk of aspiration pneumonia, increase in health-care cost and increase in…
ID
Bron
Verkorte titel
Aandoening
multiple sclerosis, dysphagia, swallowing disorders, NMES
multiple sclerose, dysfagie, slikproblemen, NMES
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
A protocol to determine optimal electrode placement and neuromuscular electrical stimulation parameters for NMES for
dysphagia in individual MS patients.
Achtergrond van het onderzoek
This study will allow the investigation of the optimal parameters of neuromuscular electrical stimulation (NMES) in MS patients. We aim to develop a protocol for NMES to determine optimal electrode placement and stimulation parameters in dysphagia MS patients. The use of NMES as treatment may prevent complications and may increase Quality of Life in MS patients with dysphagia.
Doel van het onderzoek
The reported incidence of dysphagia in multiple sclerosis (MS) varies between 33% and 90% and is higher in more disabled patients. Dysphagia is associated with an increased risk of aspiration pneumonia, increase in health-care cost and increase in mortality and a decrease of quality of life (QOL). Patients with oropharyngeal swallowing problems are commonly referred to a speech-therapist for further assessment and treatment.
Limited evidence is available for treatment of dysphagia in MS. A significant decrease of dysphagia in MS after treatment with neuromuscular electrical stimulation (NMES) was found, but in other studies the results of the effect of NMES on dysphagia were inconsistent. Therefore, the need for research into the optimal parameters for the application of NMES is clear.
Onderzoeksopzet
One timepoint of measurement: ultrasonography and NMES will be used at the same day in approximately 1 hour.
Onderzoeksproduct en/of interventie
Ultrasonography will be used to determine the location and
assess the morphology of the hyoid muscles.
Electrical stimulation will be used to stimulate the hyoid muscles.
Simultaneously, ultrasonography will be used to guide optimal electrode placement and stimulation characteristics.
Publiek
Leonie Ruhaak
[default] 2042XK
The Netherlands
+31204440763
l.ruhaak@amsterdamumc.nl
Wetenschappelijk
Leonie Ruhaak
[default] 2042XK
The Netherlands
+31204440763
l.ruhaak@amsterdamumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- > 18 years of age
- confirmed diagnosis of MS
- dysphagia characterized by incomplete hyoid movement
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- other neurological disorders
- obstruction of nasal passage
- significant cognitive deficits (has to be able to follow instructions during endoscopy and give feedback on sensing stimulation or pain in head and neck
- medically not stable enought to participate in endoscopy
- radiotherapy or oncology in head/neck area
- in case of heart problems, metal implants in head/neck area, inflamed skin, implanted stimulators or electronic devices, participation should be evaluated by a medical doctor
Opzet
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7182 |
| NTR-old | NTR7373 |
| CCMO | NL62007.029.17 |
| OMON | NL-OMON47927 |