The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are…
ID
Bron
Verkorte titel
Aandoening
Parkinson's Disease
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Probable/definite sleep bruxism and awake bruxism; temporomandibular disorders
Achtergrond van het onderzoek
Primary Objective: To investigate the prevalence of bruxism and temporomandibular disorders (TMD) in PD patients through objective measurements.
Secondary Objectives:
- To identify factors associated with a higher risk of developing the presence of TMD or bruxism.
- To investigate the salivary flow in patients with PD.
- To investigate whether the salivary flow, the pH, and the buffer capacity in patients with PD are
related to the severity of tooth wear and if this is different in patients with(out) bruxism.
- To investigate whether PD patients with bruxism differ in brain pathophysiology compared to PD
patients without bruxism.
Doel van het onderzoek
The null hypothesis will be that the prevalence of bruxism and TMD, in PD patients will be higher than in their peers without PD. Also, we hypothesized that factors as medication use, disease severity, psychosocial factors and lifestyle factors are associated.
Onderzoeksopzet
1 (+one week)
Onderzoeksproduct en/of interventie
not applicable
Publiek
M.C. Verhoeff
(020) 5980380
m.c.verhoeff@acta.nl
Wetenschappelijk
M.C. Verhoeff
(020) 5980380
m.c.verhoeff@acta.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Patients who visit the outpatient clinic for movement disorders of the VUmc hospital with (presumable) PD.
- Adults (>18 years old)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Children or adolescents (<18 years old)
- Patients with a pacemaker (only excluded for using GrindCare®)
- Patients without an available smartphone (only excluded for using the mobile application
BruxApp)
- Patients who do not fulfil the clinical diagnostic criteria for PD
- Patients with atypical parkinsonian syndromes
- Montreal Cognitive Assessment (MoCA) score < 21
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL8307 |
| Ander register | METC VUmc : 2019.143 |