COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
ID
Bron
Verkorte titel
Aandoening
Cerebral Palsy; Cerebrale Parese
Ondersteuning
University Medical Centre Groningen
Developmental Neurology (Postbox CA85)
PO Box 30.001
9700 RB Groningen
The Netherlands.
Tel: +31 50 3614252
Email: M.Hadders-Algra@med.umcg.nl
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Motor performance as measured by the Infant Motor Profile (IMP).
Achtergrond van het onderzoek
Cerebral Palsy (CP) is the most common cause of physical disability in paediatric rehabilitation. Current interventions in infants with or at high risk for CP do not have a beneficial effect on motor or cognitive performance. Theoretically however, intervention at early age when the brain is very plastic, should be more effective than intervention which starts beyond infancy. Preliminary data of an on-going project on infants with early brain dysfunction mostly not resulting in CP suggest that the new programme “Coping with and caring for infants with neurological dysfunction – a family centred program” (COPCA; Dirks & Hadders-Algra) produces better motor and cognitive outcomes at 18 months than traditional physiotherapeutic care. The present study aims at testing the effectiveness of COPCA in infants with CP.
In a randomized controlled trial 40 infants meeting strictly defined criteria indicating with high certainty the presence of CP at the corrected age of 3-9 months will receive either COPCA or traditional paediatric physiotherapy for the duration of 1 year. Infants and their parents will be assessed with a large set of tests aiming at measuring motor and cognitive function, quality of life and family related measures at baseline and at 3, 6 and 12 months after onset of intervention. In addition working mechanisms of the intervention will be studied by means of detailed analyses of postural development and quantitative video-analyses of therapeutic sessions and daily life activities.
Doel van het onderzoek
COPCA (Coping and Caring) intervention in infants at high risk for cerebral palsy will result in better functioning than Tradional Paediatric Therapy.
Onderzoeksopzet
Baseline, and after 3, 6 and 12 months.
Onderzoeksproduct en/of interventie
COPCA (Coping with and caring for infants with neurologic dysfunction; Dirks & Hadders-Algra) is a new treatment programme for children with cerebral palsy.
Publiek
P.O. Box 30.001
M. Hadders-Algra
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3614252
m.hadders-algra@med.umcg.nl
Wetenschappelijk
P.O. Box 30.001
M. Hadders-Algra
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3614252
m.hadders-algra@med.umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Infants (3-9 months corrected age) at very high risk for CP or with CP and their families.
2. Participating caregivers must have sufficient comprehension of the Dutch language.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Children with additional severe congenital disorders, such as serious congenital heart disorder
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL1368 |
NTR-old | NTR1428 |
Ander register | : 890000002 |
ISRCTN | ISRCTN wordt niet meer aangevraagd |
Samenvatting resultaten
- Dirks T, Hadders-Algra M. COPCA – Coping with and Caring for infants with neurological dysfunction – a family centered program. Handleiding, nog niet officiëel uitgeven, 2003.<br>
- Hadders-Algra M. The Neuronal Group Selection Theory: an attractive framework to explain variation in normal motor development. Dev Med Child Neurol 2000a; 42: 566-72.<br>
- Hadders-Algra M. The Neuronal Group Selection Theory: promising principles for understanding and treating developmental motor disorders. Dev Med Child Neurol 2000b; 42: 707-15.