The sugammadex dose required to achieve a TOF-ratio of 1 is not known when monitoring is not used. Administration of sugammadex based on the rocuronium dosage, while aiming for complete recovery, should reduce the risk of residual NMB.
ID
Bron
Verkorte titel
Aandoening
Residual Neuromuscular Block
Sugammadex
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Time to complete recovery of neuromuscular function after sugammadex administration.
Achtergrond van het onderzoek
The sugammadex dose required to achieve a TOF-ratio of 1 is not known when monitoring is not used. Administration of sugammadex based on the rocuronium dosage, while aiming for complete recovery, should reduce the risk of residual NMB.
Doel van het onderzoek
The sugammadex dose required to achieve a TOF-ratio of 1 is not known when monitoring is not used. Administration of sugammadex based on the rocuronium dosage, while aiming for complete recovery, should reduce the risk of residual NMB.
Onderzoeksopzet
N.A.
Onderzoeksproduct en/of interventie
None
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
->18 years
-American Society of Anesthesiologists physical status I-III
-Scheduled to undergo general anesthesia with the use of a neuromuscular blocking agent for elective surgery
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
-Neuromuscular disease
-Diabetes mellitus
-Obesity defined as a BMI >30
-Indication for a rapid sequence induction, -Expected difficult intubation or ventilation -Chronic kidney failure (EGFR <30), liver failure, pregnancy and allergy to neuromuscular blocking agent (rocuronium) or to the reversal agent (sugammadex).
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7472 |
| NTR-old | NTR7714 |
| Ander register | METC LUMC : G18.004 |