Higher order aberrations, like spherical aberration, decreases visual performance.
ID
Bron
Verkorte titel
Aandoening
Measurements in 48 healthy subjects aged 20 to 35 years (24 subjects) and 55 to 70 years (24 subjects).
Ondersteuning
Hanzeplein 1
Postbus 30.001
9700 RB Groningen
The Netherlands
Tel: (+31)050-3612510
Fax: (+31)050-3611709
AMO (advanced medical optics) Groningen B.V.
Van Swietenlaan 5
9728 NX Groningen
Tel: (+31)050-5296600
Fax: (+31)050-5267860
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Selection of the contrast sensitivity test which predicts the spherical aberration most reliably.
Achtergrond van het onderzoek
The relation between contrast sensitivity and spherical aberration and other higher order aberrations (RMS) will be studied in young and elderly subjects without ocular pathology. Contrast sensitivity will be assessed with the use of eight different contrast sensitivity tests at optimal focus and at positive and negative defocus. These results will be related to the higher order aberrations of the eyes.
Doel van het onderzoek
Higher order aberrations, like spherical aberration, decreases visual performance.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Best corrected visual acuity was determined with an ETDRS chart and the spherical aberration (SA) was measured with a wavefront analyzer (WASCA version 1.26.3, Asclepion Meditec, Jena, Germany).
The contrast sensitivity is measured with two computerized tests:
1. One with vertical sine-wave gratings (1.5-12 cpd) generated on a CRT (Cambridge Research Systems, Rochester, UK; Von Bekesy tracking method);
2. The Holladay sine-wave (1.5 -18 cpd) modulated circular lines (HACSS) (M&S Technologies, Skokie, Illinois, USA), and with six contrast sensitivity chart tests:
1. Pelli Robson contrast sensitivity test;
2. low contrast ETDRS-like optotype chart 2.5%;
3. Low contrast ETDRS-like optotype chart 10%;
4. Edge contrast sensitivity test: GECKO;
5. Edge contrast sensitivity test: GECKO-100;
6. Vector Vision. Contrast sensitivity is measured in mesopic (3 cd/m2) and photopic (160 cd/m2) conditions, using only the dominant eye.
Tests were performed at optimal refractive state of the eye and at a variety of defocus situations(-2D to 2D).
Publiek
Groningen (UMCG), Department Ophtalmology,
P.O. box 30.001
K.W. Gaalen, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3619692
k.van.gaalen@ohk.umcg.nl
Wetenschappelijk
Groningen (UMCG), Department Ophtalmology,
P.O. box 30.001
K.W. Gaalen, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3619692
k.van.gaalen@ohk.umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
No ocular pathology.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Refractive correction larger than +/- 2 D;
2. Cylindrical correction larger than 1.5 D;
3. Cylindrical axis more then 20ยบ from the horizontal or vertical axis.
Opzet
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In overige registers
Register | ID |
---|---|
NTR-new | NL799 |
NTR-old | NTR812 |
Ander register | : 1 |
ISRCTN | ISRCTN66724598 |