The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent…
ID
Bron
Verkorte titel
Aandoening
Carbon monoxide, compound A, Anesthesia, Carbon dioxide absorbents, Desiccation. Koolmonoxide, Anesthesie, Kooldioxide absorbers, Uitdroging.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Amount of carbon monoxide or compound A produced.
Achtergrond van het onderzoek
All modern vapor anesthetics are capable of carbon monoxide (CO) production as a result of interaction with desiccated strong base containing carbon dioxide absorbents. In desiccated absorbents, desflurane produces the highest concentrations of CO. Sevoflurane is known to produce the nephrotoxic compound A (CA) independent of the water content of the carbon dioxide absorbent. The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol adapted from Woehlck et al., developed to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus® while still maintaining the possibility of flushing the ventilating circuits of the anesthesia machines with a flow of air.
Doel van het onderzoek
The purpose of this study is to register the average CO concentrations in forty patients receiving desflurane or sevoflurane anesthesia after implementation of a safety protocol to prevent desiccation of the strong base containing absorbent Drägersorb 800 Plus®.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Desflurane or sevoflurane anesthesia.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Non-smoking patients;
2. American Society of Anesthesiologists physical status class 1 to 3
scheduled for a surgical procedure that would last at least ninety minutes.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Younger than 18 years of age;
2. Suffering from terminal renal failure.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL955 |
| NTR-old | NTR981 |
| Ander register | : |
| ISRCTN | ISRCTN84188372 |