Heart rate variability measures correlate with pain intensity in patients with advanced cancer.
ID
Bron
Verkorte titel
Aandoening
Patients with malignancy visiting our outpatient clinic who have a pain intensity of at least 5 on a visual analogue scale (ranging from 0-10) can be included.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Correlation between the pain intensity as measured by the visual analogue scale and as measured by heart rate variability.
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
Heart rate variability measures correlate with pain intensity in patients with advanced cancer.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Heart rate variability measurements will be performed on day 0 (before start of pain medication), day 2 and day 7.
Publiek
[default]
The Netherlands
Wetenschappelijk
[default]
The Netherlands
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Patients with known metastatic malignancy;
2. Patients with a pain intensity of at least 5 on a visual analogue pain scale;
3. Patients able to have heart rate measures taken;
4. Patients able to fill in the EORTC QLQ-C30;
5. Patients should have sinus rhythm;
6. Performance score 0, 1 or 2;
7. Informed consent should be given.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Patients with neuropathic pain;
2. Patients using medication that interferes with HRV;
3. Patients who have hemodynamically significant cardiac valvular abnormalities, severe chronic heart failure (NYHA III-IV), a history of vagotomy or sympathectomy;
4. Patients with other conditions / illnesses that can influence autonomic function;
5. Patients with brain metastases;
6. Patients who are treated with chemotherapy;
7. Patients who will start with chemotherapy and/or radiotherapy within the week of the study.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL600 |
| NTR-old | NTR656 |
| Ander register | : N/A |
| ISRCTN | Incomplete info for ISRCTN |