To validate in vivo the velocity offset correction method as published by Walker PG et al. (JMRI 3, 521 1993) such that it can assure velocity offsets < 0.6 cm/s at the ascending aorta and pulmonary artery for 2D through-plane phase contrast MRI…
ID
Bron
Aandoening
Blood flow measurement with MRI in the large vessel around the heart (aorta and pulmonary artery) show a measurement error; a velocity offset in the data.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The primary study outcome parameter is the velocity offset in cm/s at the location of the aorta or pulmonary artery.
Doel van het onderzoek
To validate in vivo the velocity offset correction method as published by Walker PG et al. (JMRI 3, 521 1993) such that it can assure velocity offsets < 0.6 cm/s at the ascending aorta and pulmonary artery for 2D through-plane phase contrast MRI velocity measurements at different centers and for different vendors.
Onderzoeksopzet
There will an analysis at the end of the inclusion periode, at about 1 year.
Onderzoeksproduct en/of interventie
Observational study.
Seperate phantom measurements will be obtained after an in vivo clinical MRI scan.
Publiek
VU University Medical Center
P.O. Box 7057, 1007 MB Amsterdam, the Netherlands
M.B.M. Hofman
de Boelelaan 1117
Amsterdam
The Netherlands
+31-20-4444 593
mbm.hofman@vumc.nl
Wetenschappelijk
VU University Medical Center
P.O. Box 7057, 1007 MB Amsterdam, the Netherlands
M.B.M. Hofman
de Boelelaan 1117
Amsterdam
The Netherlands
+31-20-4444 593
mbm.hofman@vumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Informed consent
- Sinus rhythm at CMR examination
- 2D flow acquisitions by MRI at the aorta or pulmonary artery without spatial infolding artefacts.
- MRI acquisition on MRI system by Siemens: Magnetom Avanto, VB17 or newer 1.5 T systems such; for GE: Signa Excite (HDx 15M4) or newer as the Optima MR360; and for Philips: Achieva R2.6.3 or newer as the Ingenia.
- MRI flow acquisitions with the general accepted standard settings
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Incapacitated adults.
- Lack of a phantom measurement within the protocol specifications.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4720 |
| NTR-old | NTR4865 |
| Ander register | : None available |