Reproductive outcomes in women with fibroids or after removal of fibroids: a retrospective cohort study.

Patients with asymptomatic myomas have a reduced risk of spontaneous pregnancy and an increased risk of premature birth and miscarriages. However, the extent of this effect is still insufficiently known, because the literature often does not include the type, number and localization of the myoma(s). Surgical treatment of myomas are frequently performed to treat gynecological complaints and/or improve pregnancy outcomes. The long-term outcomes of these interventions have not been sufficiently investigated with regard to the reproductive outcomes. These results are important for counseling patients considering such an intervention, but also for setting up a future (randomized) study.
The primary objective is to study pregnancy outcomes in patients with asymptomatic myomas without further interventions related to spontaneous pregnancy and an increased risk of premature birth and miscarriages. We want to see if number, localization, size, and type of myoma influences these outcomes. We want to investigate the same in women who have had a myoma treatment. We want to look both at women who have had surgical treatment on the myomas to promote fertility outcomes and also at women who received this from gynecological complaints.

Surgical treatment of myomas can have a positive effect on the tome until ongoing pregnancy and decrease the risk of premature birth and miscarriages, but is depended on number, localization, size, and type of myoma.

One survey with questions about complaints, pregnancy and treatment of myomas.