It is hypothesized that the ingestion of plant based proteins will result in a similar muscle protein synthetic response compared to animal based proteins.
ID
Bron
Verkorte titel
Aandoening
Muscle metabolism
Protein
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Primary study parameter is myofibrillar protein synthesis rate.
Achtergrond van het onderzoek
Skeletal muscle mass maintenance is regulated by two main anabolic stimuli, food intake and physical activity. Dietary protein intake directly stimulates muscle protein synthesis rates and inhibits muscle protein breakdown. Therefore, the post-prandial muscle protein synthetic response to feeding plays a key regulatory role in skeletal muscle mass maintenance.
The capacity of dietary protein to stimulate post-prandial muscle protein accretion varies between protein sources. More than half of the total amount of dietary protein that is consumed by humans worldwide is of plant origin, with plant based proteins providing up to 80% of dietary protein consumed in less developed regions. Overall it is assumed that plant based proteins are less potent in stimulating post-prandial muscle protein synthesis. However, the anabolic properties of plant based protein sources have hardly been assessed. Therefore, this project will investigate the anabolic properties of plant based proteins.
Doel van het onderzoek
It is hypothesized that the ingestion of plant based proteins will result in a similar muscle protein synthetic response compared to animal based proteins.
Onderzoeksopzet
Blood and muscle samples will be collected at regular time intervals.
Onderzoeksproduct en/of interventie
Subjects will consume 30 g of protein in the form of a beverage.
Publiek
Philippe Pinckaers
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
0031 43 388 2215
philippe.pinckaers@maastrichtuniversity.nl
Wetenschappelijk
Philippe Pinckaers
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
0031 43 388 2215
philippe.pinckaers@maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Male
- Aged 18-35 y inclusive
- BMI 18.5 – 27.5 inclusive
- Healthy recreationally active
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Females
- Wheat allergy
- Celiac disease
- Allergies to milk proteins
- Lactose intolerance
- Smoking
- Diagnosed diabetes
- Diagnosed metabolic or intestinal disorders
- A history of neuromuscular problems
- Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
- Participation in structured resistance exercise program
- Previous participation in a 13C amino acid tracer study within the last 1 year
Opzet
Deelname
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