Fracture healing study.

1. Postmenopausal women older than 50 years with a stable distal radius fracture that is treated by immobilization with a cast;

2. Patients who understand the conditions of the study and are willing and able to comply with the scheduled evaluations and rehabilitation;

3. Patients who signed the informed consent form prior to inclusion.

1. Patients with a history of surgery of the wrist or radius at the fractured side or who need surgery this time;

2. Patients with an active or suspected infection in the last 3 months prior to the fracture;

3. Patients with malignancy in the last 12 months;

4. Patients with a neuromuscular or neurosensory deficit which would limit the ability to assess the performance during the healing period;

5. Patients with known systemic or metabolic disorders leading to progressive bone deterioration, such as: hyperthyroidism; hyperparathyroidism; chronic kidney disease with eGFR<30 ml/min; sarcoidosis; hypercalcemia;

6. Patients with an active inflammatory disease during the last 12 months, such as: reumatiod arthritis; systemic lupus erythematosus; inflammatory bowel disease;

7. The use of glucocorticoids during the last 12 months;

8. Patients who, as judged by the prinicipal investigator, are mentally incompetent or are unlikely to be compliant with the follow-up evaluation schedule.