The percentage of receptors responsible for sensibility in the breast (and nipple) differ from the percentage of receptors in the abdominal skin.
ID
Bron
Verkorte titel
Aandoening
sensibility breast, sensibility abdomen, breast reconstruction, breast cancer, receptor
Ondersteuning
Maastricht University Medical Centre
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
percentage of receptors responsible for the sensiblity in the skin.
Achtergrond van het onderzoek
By taking biopsies of the skin of the breast and the abdomen we will analyze the difference in percentages of receptors responsible for the sensibility. This can be of great value for the expected results concerning the sensibility after a breast reconstruction.
Doel van het onderzoek
The percentage of receptors responsible for sensibility in the breast (and nipple) differ from the percentage of receptors in the abdominal skin.
Onderzoeksopzet
biopsy during the operation.
Onderzoeksproduct en/of interventie
During the mastectomy 6 biopsies of 5mm will be taken of the skin that will be removed during the mastectomy.
During the abdominal surgery (DIEP, lowerbodylift, abdominoplasty) 2 biopsies of 5mm will be taken of the skin that will be removed during this surgery.
The biopsies will be analyzed and the percentage of receptors responsible for the sensbility in the skin will be compared.
Publiek
Nadine Hillberg
Postbus 5500
Sittard-Geleen 6130 MB
The Netherlands
0031648531220
n.hillberg@zuyderland.nl
Wetenschappelijk
Nadine Hillberg
Postbus 5500
Sittard-Geleen 6130 MB
The Netherlands
0031648531220
n.hillberg@zuyderland.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
-female - Age of at least 18 years
- Mastery of the Dutch language in word and writing.
- Informed consent for participation in the research
- biopsy of the tissue is possible from the tissue that will be removed during a mastectomy or abdominal operation (lowerbodylift, DIEP or abdominoplasty)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- clinical abnormalities are visible on the nipple
- Mastitis, ulcerations on the breast or a T4-tumor. r.
- Suspicion of M. Paget
- On imaging the tumor is located in less than 2cm distance of the nipple.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL7281 |
| NTR-old | NTR7514 |
| Ander register | : METCZ20180082 |