The application of dual site tACS during cognitive training ameliorates spatial neglect symptoms to a larger extent than the application of sham stimulation during cognitive training.
ID
Bron
Verkorte titel
Aandoening
Stroke patients with unilateral spatial neglect
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Performance on a digitalised Star Cancellation Test
Achtergrond van het onderzoek
Hemispatial neglect is a common symptom in stroke patients and is marked by the inability to attend to the contralesional side of space. The standard cognitive training for neglect in the subacute phase of stroke is visual scanning training (VST). However, VST requires many sessions to have a long-lasting effect. Here, we aim to increase the effectiveness of VST by applying non-invasive brain stimulation, namely transcranial Alternating Current Stimulation (tACS), to the frontoparietal attention network in patients with neglect following subacute stroke.
Doel van het onderzoek
The application of dual site tACS during cognitive training ameliorates spatial neglect symptoms to a larger extent than the application of sham stimulation during cognitive training.
Onderzoeksopzet
Unkwown
Onderzoeksproduct en/of interventie
We will combine an evidence based Visual Scanning Training with 40 minutes of (active or sham) dual site tACS at the theta (6 Hz) and gamma (80 Hz) frequencies. The intervention is administered 5 times a week for a duration of 2 weeks.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
• 30-80 years of age
• Subacute stroke (stroke occurred more than 2 weeks and less than 6 months ago; first or recurrent, ischemic or intracerebral haemorrhagic lesion)
• Diagnosed visuospatial neglect and/or spatial neglect symptoms (either left or right sided) on the basis of clinical judgement (i.e. by the cooperating clinical (neuro)psychologist).
• Sufficient comprehension and communication skills to benefit from training (based on clinical judgement)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
• Physically or mentally unable to participate (e.g. to perform the neglect training)
• Severe communicative disability, including aphasia
• Local scalp injuries
• Eczema on scalp or psoriasis
• (Neuro)psychiatric or neurodegenerative diseases including dementia, serious depression, multiple sclerosis, Parkinson’s disease, Huntington’s disease on the basis of clinical judgement (i.e. cooperating (neuro)psychologist)
• Current alcohol and/or drug abuse or a history of abuse within the last 6 months
• Pregnancy
Opzet
Deelname
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| Register | ID |
|---|---|
| NTR-new | NL8145 |
| Ander register | METC : METC 19-081 |