Intestinal tissue oxygen extraction, IFABP levels and plasma citrulline levels relate to time to full enteral feeding after Necrotizing Enterocolitis in preterm infants
ID
Bron
Verkorte titel
Aandoening
necrotizing enterocolitis
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Our main study parameters are based on the following questions:<br>
- Intestinal oxygen saturation (and extraction) measured with NIRS and the time it takes to reach full enteral feeding after developing NEC<br>
- The measurement of urinary I-FABPs and the time it takes to reach full enteral feeding after developing NEC <br>
- The measurement of plasma citrulline and the time it takes to reach full enteral feeding after developing NEC
<br><br>
Our main study parameters consist of:<br>
- Intestinal oxygen saturation (rintSO2) <br>
- Intestinal FTOE<br>
- Concentration of urinary I-FABP<br>
- Plasma Citrulline levels
Doel van het onderzoek
Intestinal tissue oxygen extraction, IFABP levels and plasma citrulline levels relate to time to full enteral feeding after Necrotizing Enterocolitis in preterm infants
Onderzoeksopzet
NA
Onderzoeksproduct en/of interventie
none: observational
Publiek
kinderarts-neonatoloog, afdeling neonatologie
Beatrix Kinderziekenhuis, UMC Groningen
Huispostcode: CA 51
Hanzeplein 1
Postbus 30001
Groningen 9700 RB
The Netherlands
050-3614215
e.kooi@umcg.nl
Wetenschappelijk
kinderarts-neonatoloog, afdeling neonatologie
Beatrix Kinderziekenhuis, UMC Groningen
Huispostcode: CA 51
Hanzeplein 1
Postbus 30001
Groningen 9700 RB
The Netherlands
050-3614215
e.kooi@umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
In order to be eligible to participate in this study, a subject must meet all of the following criteria: Infants with a gestational age <37 weeks with confirmed pneumatosis intestinalis on x-ray, or suspected NEC > Bells stage 1, admitted on the NICU in Groningen.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Large chromosomal abnormalities
- Intraventricular hemorrhage/Perventricular hemorrhage >grade 2
- Use of dexamethason
- Congenital heart deformities other than patent ductus arteriosus
- Abdominal wall defects/other congenital gastroenteral deformities (ie atresia, microcolon)
- Parents/caretakers who are unable to understand Dutch or English
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4664 |
| NTR-old | NTR4816 |
| Ander register | : METc2014/283 |