In patients with non-insulin dependent type 2 diabetes, intensive, short term physical activity is associated with decreased blood glucose levels and number of cardiovascular complications. In patients who are insulin dependent however, the effects…
ID
Bron
Verkorte titel
Aandoening
physical activity
insulin dependent type 2 diabetes
behavior change
Ondersteuning
Department of internal medicine
Slotervaarthospital
Louwesweg 6
1006 BK Amsterdam
The Netherlands
Tel: +3120-5129333
Web: www.slz.nl
Flemingweg 18
2408 AV Alphen a/d Rijn
The Netherlands
Tel: +31172-449494
Web: www.novonordisk.nl
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Primary outcome measure was:<br>
- the change in physical activity measured by the Tecumseh/Minnesota scale.
Achtergrond van het onderzoek
Objective: In patients with non-insulin dependent diabetes type 2, intensive, short term physical activity is associated with decreased blood glucose levels and number of cardiovascular complications. In patients who are insulin dependent however, the effects of physical activity are less clear. Moreover, short-term, intensive lifestyle interventions often fail to significantly improve physical activity in the long term. The aim of this study was to determine the sustainability and effects upon physical activity and effects on HbA1c levels and other clinical parameters of diabetes of a 2-year behavior intervention program in insulin dependent patients with diabetes type 2.
Doel van het onderzoek
In patients with non-insulin dependent type 2 diabetes, intensive, short term physical activity is associated with decreased blood glucose levels and number of cardiovascular complications. In patients who are insulin dependent however, the effects of physical activity are less clear since few studies are conducted with only insulin dependent type 2 diabetes patients included. Moreover, short-term, intensive lifestyle interventions often fail to significantly improve physical activity in the long term because of high drop out rates. The aim of this study was to determine the sustainability and effects upon physical activity, HbA1c levels and other clinical parameters of type 2 diabetes of a 2-year, behavior intervention program in insulin dependent type 2 diabetes patients.
Onderzoeksopzet
The inclusion period was 1 year, from juli 2005 until juli 2006.
Measurements of every individual were performed at baseline and after 1 and 2 years.
The study was finished in august 2008.
Onderzoeksproduct en/of interventie
The intervention program was based on the PACE (Physician-based Assessment and Counseling for Exercise) program; to stimulate exercise in participants on low profile by written information, short personal advise and telephone follow-up.
The program consisted of 4 visits per year at the physiotherapist and a 15-minute telephone call 6 weeks after each visit.
In the first consult, the physiotherapist and the subjects made a personal exercise program together based on the persons¡¯ baseline exercise pattern, medical condition, exercise tolerance and personal preferences.
The goal was for the participants to exercise at a medium intensive level, 160-180 minutes per week and spread over at least three times per week, based on the Diabetes Prevention Program.
During the following contacts, the subjects were instructed and encouraged to achieve or maintain the intended goal.
Participants in the control group received no individual advice, no programs were provided and no additional appointments were scheduled, apart from the visits for the annual measurements.
Publiek
Department of internal medicine <br>
Diabetespoliclinic
Willeke Wisse
Louwesweg 6
Amsterdam 1006 BK
The Netherlands
3120-5129333
willekewisse@xs4all.nl
Wetenschappelijk
Department of internal medicine <br>
Diabetespoliclinic
Willeke Wisse
Louwesweg 6
Amsterdam 1006 BK
The Netherlands
3120-5129333
willekewisse@xs4all.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. A clinical trial involving patients at the Dutch Slotervaart Hospital, who had type 2 diabetes and were using insulin.
Subjects aged until 70 years and exercising less than 180 minutes per week, spread over at least three times per week, were included to the study.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Eligible persons were excluded if they met one of the following conditions:
1. Poor knowledge of the Dutch language
2. Life-expectancy of less than 5 years
3. Clinical manifest cardiovascular disease (hospitalization as a result of heart disease until 6 months before inclusion
4. Angina pectoris class ¡Ý II (NYHA)
5. Left heart-block or aorta-stenosis)
6. Pregnant women
7. Repeated hospitalization because of recurrent hypoglycaemia
8. Pre-terminal kidney-failure
9. Proliferative retinopathy
10. Usage of an insulin pump
11. Revalidation therapy
12. Psychiatric diseases
13. Chronic alcohol and/or drugs abuse
14. Decreased physical tolerance because of unrelated diabetic co-morbidity, like COPD or immune diseases.
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL1440 |
NTR-old | NTR1501 |
Ander register | Number MECC Slotervaarthospital : 0436 |
ISRCTN | ISRCTN wordt niet meer aangevraagd |