Short-term exercise and protein supplementation enhances muscle strength, mass and physical fitness in a group of untrained men and women aged 55-75 years.
ID
Bron
Verkorte titel
Aandoening
low muscle strength, low muscle mass, low physical fitness, sarcopenia, aging process
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The primary outcome of this study is the change in isometric quadriceps strength (Biodex).
Achtergrond van het onderzoek
Rationale and objective:
The aging process and physical inactivity are both clearly linked to low muscle mass, muscle strength and physical fitness. Long-term exercise programs in combination with protein supplementation show improvements in muscle function. However, in some circumstances such as prior surgery, time available to improve person’s muscle function and physical fitness is limited to a few weeks. Therefore, the present study aims to investigate whether an improvement in muscle strength, muscle mass and physical fitness can be achieved within 4 weeks of exercise and protein supplementation in a group of untrained men and women aged 55-75 years.
Study design:
Single group repeated measures design.
Study population:
18 untrained men and women aged 55 to 75 years who do not meet the Dutch Norm for Health-enhancing Physical Activity ('Nederlandse Norm Gezond Bewegen').
Intervention:
4 weeks of exercise and protein supplementation
Main study parameters:
Changes in quadriceps strength, quadriceps muscle mass, handgrip strength, power of the lower limb, physical fitness, habitual physical activity and daily protein intake. Parameters are assessed at baseline, 2 weeks and 4 weeks.
Doel van het onderzoek
Short-term exercise and protein supplementation enhances muscle strength, mass and physical fitness in a group of untrained men and women aged 55-75 years.
Onderzoeksopzet
Parameters are assessed at baseline, 2 weeks and 4 weeks.
Onderzoeksproduct en/of interventie
All subjects will receive a 4 week intervention program consisting of:
1) an exercise program (combination of resistance and aerobic exercises during supervised exercise sessions, and a home-based advice)
2) protein supplementation.
Publiek
Margot de Regt
Postbus 902
Ede 6710 HN
The Netherlands
T: 0318-434383
E: RegtM@zgv.nl
Wetenschappelijk
Margot de Regt
Postbus 902
Ede 6710 HN
The Netherlands
T: 0318-434383
E: RegtM@zgv.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Aged 55 to 75 years.
- Not meeting the Dutch Norm for Health-enhancing Physical Activity ('Nederlandse Norm Gezond Bewegen').
- No participation in any structured or regular exercise training programs for the last 3 months.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Allergic or sensitive for milk proteins, or lactose intolerant.
- Diagnosed with renal insufficiency.
- On a diet which affects protein intake (i.e. advices of an increase, decrease or type of protein (intake)).
- Having known contraindications for exercise.
- Diagnosed with cancer for which currently treated.
- Having a contraindication to MRI scanning (including, but not limited to):
o pacemakers and defibrillators
o intraorbital or intraocular metallic fragments
o ferromagnetic implants
o claustrophobia
- Participation in another intervention trial.
- Unable to understand Dutch.
Opzet
Deelname
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