The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
ID
Bron
Verkorte titel
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Change of time constant of O2 onset or recovery kinetics > 10 sec.
Achtergrond van het onderzoek
Oxygen uptake kinetics provide objective information on the ability to adapt to and recover from exercise that is indicative of daily life in patients with chronic heart failure. Therefore this parameter is potentially useful for measuring effects of exercise training in these patients. The main goal of this study is to determine the effects of exercise training on O2 onset and recovery kinetics in patients with chronic heart failure.
Doel van het onderzoek
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Exercise training (12 weeks) versus standard care.
Publiek
P.O. Box 7777
Hareld M.C. Kemps
Veldhoven 5500 MB
The Netherlands
+31 (0)40 8888620
H.Kemps@wxs.nl
Wetenschappelijk
P.O. Box 7777
Hareld M.C. Kemps
Veldhoven 5500 MB
The Netherlands
+31 (0)40 8888620
H.Kemps@wxs.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Stable CHF (NYHA class II-III and echocardiographical ejection fraction <= 40%) attributed to idiopathic dilated cardiomyopathy or ischemic heart disease due to myocardial infarction.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Myocardial infarction / unstable angina pectoris in previous 3 months;
2. Atrial fbrillation / flutter;
3. COPD (Tiffenau index < 60%).
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL576 |
| NTR-old | NTR632 |
| Ander register | : N/A |
| ISRCTN | ISRCTN66318889 |