Feasibility and accuracy of the Olympus Extra Wide Angle View colonoscope for the detection of colorectal lesions in comparison with the Exera III study

- Age greater than or equal to 18 years

- High risk for colorectal cancer: FOBT positive, personal or familial (first degree relatives) history of colorectal cancer or colorectal adenoma, patients with symptoms suggestive of colorectal neoplasm: rectal bleeding, recent change in frequency and consistency of stools.

- Status 1 and 2 of the ASA classification (see Appendix I)

- Signed informed consent

- Mental or physical condition that can adversely affect the preparation or conduct of the examination or which precludes compliance with the study and / or device instructions.

- Inability to undergo bowel cleansing for colonoscopy.

- Prior abdominal surgery of the gastrointestinal tract (other than uncomplicated appendectomy or cholecystectomy).

- Known or suspicion of inflammatory bowel disease.

- Known large (> 2 cm) colorectal polyp for polypectomy

- Colonic diverticulosis complication within 3 months prior inclusion.

- Very high risk for colorectal cancer, history of extensive polyposis, patients with known genetic disease (Familial Adenomatous Polyposis (FAP), Hereditary Non-Polyposis Colorectal Cancer (HNPCC)).

- Coagulation abnormalities or taking drugs affecting coagulation.

- Life threatening conditions

- Status > 2 of the ASA classification (see Appendix I).

- Renal insufficiency or any contraindication or medication contraindicating the administration of bowel cleansing.

- Female patients who are pregnant or nursing, or of childbearing potential and are not using adequate contraception.

- Participation in another clinical trial within 30 days prior to the Screening Visit or during this study.