Influenza-like-illness (ILI) is not only caused by an influenza virus infection, but also by other pathogens, both viral and bacterial. In this study nose and throat swab samples will be taken during ILI episodes to identify pathogens causing ILI in…
ID
Bron
Verkorte titel
Aandoening
infectious diseases, influenza, viral and bacterial co-infections, carriage
(in Dutch: infectieziekten, griep, virale en bacteriele infecties, dragerschap)
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Presence of influenza A and B virus in nasal swab during ILI episodes.
Achtergrond van het onderzoek
The general public is questioning the effectiveness of seasonal influenza vaccination in elderly as a result of the general impression that all influenza-like illness (ILI) is caused by an influenza virus infection. However, several pathogens, both viral and bacterial, can cause ILI. A better understanding of the percentage of ILI caused by an influenza virus infection and the contribution of other respiratory viruses or involvement of bacteria will allow a better appreciation of seasonal influenza vaccines. In addition, information will be collected on the occurrence of viral and bacterial co-infections.
Doel van het onderzoek
Influenza-like-illness (ILI) is not only caused by an influenza virus infection, but also by other pathogens, both viral and bacterial. In this study nose and throat swab samples will be taken during ILI episodes to identify pathogens causing ILI in the elderly population.
Onderzoeksopzet
Timepoint 1: Within 72 hours after onset of fever and at least 1 other ILI symptom;
Timepoint 2: 8 weeks after timepoint 1;
Extra timepoint: Any timepoint in subjects who do not (yet) have ILI symptoms during the influenza season.
Onderzoeksproduct en/of interventie
N/A
Publiek
R.A.J. Boxtel, van
Bilthoven 3721 MA
The Netherlands
+31 (0)30 2742755
renee.van.boxtel@rivm.nl
Wetenschappelijk
R.A.J. Boxtel, van
Bilthoven 3721 MA
The Netherlands
+31 (0)30 2742755
renee.van.boxtel@rivm.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. ≥ 60 years of age;
2. Willing to present when influenza-like-illness (ILI) symptoms occur;
3. Signed Informed Consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
N/A
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL3234 |
| NTR-old | NTR3386 |
| Ander register | ABR / protocol ID : 37392 / VAC-261; |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |