MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
ID
Bron
Aandoening
Post-mortem radiology. Whole-body MRI. Whole-boy CT. Whole-body imaging. CT-guided biopsy. MIA: diagnostic performance. Image-guided biopsy. Stereotactic brain biopsy. Conventional autopsy. Alternative autopsy.
Ondersteuning
Stichting Coolsingel
KWF kankerbestrijding
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Agreement between MIA and CA for cause of death and sensitivity and specificity of major and overall findings
Doel van het onderzoek
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
Onderzoeksopzet
Not appicable
Onderzoeksproduct en/of interventie
We performed MIA followed by CA the following day. Both the MIA investigators and CA pathologists who performed the autopsy received the same clinical information and were blinded to each other's findings.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Deceased adult patients, written informed consent from next of kin, availability of imaging equipments and technologists
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
forensic causes of death, known or suspected “high-risk” infected cadavers (hepatitis C, human immunodeficiency virus, tuberculosis), open abdominal wounds and body size too large for imaging equipment.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4732 |
| NTR-old | NTR5072 |
| Ander register | : MEC-2011-055 |