Motor cortex or cerebellar tDCS(transcranial Direct Current Stimulation) will enhance motor skill learning in heatlhy subjects and chronic stroke survivors. Stimulating the motor cortex will result in an increase in offline learning, whereas…
ID
Bron
Aandoening
tDCS
Stroke
motor skill learning
Dutch:
tDCS
CVA
motorisch leren
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Relative change in motor skill between the first and last training block (total learning).
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From the first and last training block of every training session the mean movement time and the error rate is calculated. By combining these two parameters with the SAF the motor skill of these two blocks are calculated. The motor skills from all training sessions together are used to calculate the main parameter total learning and the secondary parameters on- and offline learning.
Achtergrond van het onderzoek
The primary objective of this study is to assess whether anodal motor cortex- or anodal cerebellar tDCS can enhance motor skill learning in the lower extremities in chronic stroke survivors and healthy subjects.
This study is a double blind randomized controlled trial. All subjects participate in three experimental training sessions on consecutive days and receive tDCS during the first 10 minutes of every training session. Every experimental group receives one type of stimulation, being anodal motor cortex stimulation, anodal cerebellar stimulation or sham (placebo) stimulation.
It is of importance to conduct this study to know whether tDCS results in any beneficial lasting effects on motor learning. If so, the role of different brain areas in motor skill learning will be better understood and in future studies we can try to maximize these beneficial effects on rehabilitation of walking.
Doel van het onderzoek
Motor cortex or cerebellar tDCS(transcranial Direct Current Stimulation) will enhance motor skill learning in heatlhy subjects and chronic stroke survivors. Stimulating the motor cortex will result in an increase in offline learning, whereas stimulating the cerebellum will result in an increase in online learning.
Onderzoeksopzet
Total learning: after day 3
Online learning: After day 1,2,3
Offline learning: After day 2,3
Onderzoeksproduct en/of interventie
Subjects will participate in three training sessions and receive tDCS (transcranial Direct Current Stimulation) during the first 10 minutes of every training session. Every experimental group receives one type of stimulation, being anodal motor cortex stimulation, anodal cerebellar stimulation or sham (placebo) stimulation.
Publiek
Edwin Asseldonk, van
Enschede 7500 AE
The Netherlands
+31 (0)53 4892446
e.h.f.vanasseldonk@utwente.nl
Wetenschappelijk
Edwin Asseldonk, van
Enschede 7500 AE
The Netherlands
+31 (0)53 4892446
e.h.f.vanasseldonk@utwente.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
For healthy subjects:
1. Age > 18 years;
2. Able to stand and make stepping movements for in total 42 minutes;
3. Good vision (on 2 m distance).
Additional for stroke patients:
1. Diagnosed with a hemiparesis as the result of a first ever, ischemic subcortical stroke;
2. Chronic stage: time since stroke > 6 months;
3. Independent walkers with clear walking impairment.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Metallic implants in the brain;
2. Presensce of severe or frequent headache;
3. Other neurological disorders or orthopedic problems;
4. Have a history of cardiac conditions that interfere with physical load.
Opzet
Deelname
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In overige registers
Register | ID |
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NTR-new | NL3171 |
NTR-old | NTR3315 |
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