Beer induces more bloating than carbonated soft drinks and this effect is more prominent in women compared to men as measured from theh stomach and in regional brain activation.
ID
Bron
Verkorte titel
Aandoening
Bloating, dyspepsia
Opgeblazen gevoel, dyspepsia, maagklachten
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1) Gastric measures (MRI): Gastric volume, air and liquid gastric compartments.<br>
2) Subjective ratings of fullness and bloating.<br>
3) Changes in regional brain activity
Doel van het onderzoek
Beer induces more bloating than carbonated soft drinks and this effect is more prominent in women compared to men as measured from theh stomach and in regional brain activation.
Onderzoeksopzet
Two study days.
Onderzoeksproduct en/of interventie
Consumption of 500 mL beer or carbonated soft drink.
Publiek
Jac Niessen
Corporate Communicatie
Postbus 9101, 6700 HB Wageningen
Wageningen 6702 PB
The Netherlands
Tel. 0317 485003
jac.niessen@wur.nl
Wetenschappelijk
Jac Niessen
Corporate Communicatie
Postbus 9101, 6700 HB Wageningen
Wageningen 6702 PB
The Netherlands
Tel. 0317 485003
jac.niessen@wur.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
-Age: 18-40 years
-BMI: 18.5 – 25.0 kg/m2
-Healthy (as judged by the participant)
-On average consuming more than 1 unit of beer per month but less than 13 units per week.
-On average consuming more than 1 unit of soft drink per month but less than 13 units per week.
-Willing to be informed about incidental findings of pathology and approving of reporting this to their general physician.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
-Drug use or medical conditions which may interfere with normal functioning of the digestive tract.
-Drug use or
medical conditions which may interfere with normal functioning of the circulatory system
-Drug use or medical conditions which may lead to unreliable fMRI results (including, but not limited to
neurological conditions)
-Reported unexplained weight loss or weight gain of > 5 kg in the month prior to pre-study screening
-For women: having the intention to become pregnant, pregnancy during the last 6 months or lactating
- Smoking on average more than one cigarette/cigar a day
-Having a contra-indication to MRI scanning including, but not limited to, metal in the body and claustrofobia
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5309 |
| NTR-old | NTR5418 |
| Ander register | NL54050.081.15 : CCMO |