The hypotheses of the study is that TARC levels in patients with fever, other causes of lymphadenopathy and non-Hodgkin lymphoma will be significantly lower compared to patients with Hodgkin lymphoma.
ID
Bron
Verkorte titel
Aandoening
-lymphadenopathy
-fever
-
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Mean TARC levels (pg/mL) in correlation with final diagnosis
Achtergrond van het onderzoek
This is a prospective study to determine TARC levels in patients with lymph node enlargement of unknown origin, fever and in patients who are already diagnosed with non-Hodgkin lymphoma subtypes. TARC levels will be matched with final diagnosis and compared with TARC levels of healthy controls and patients with Hodgkin lymphoma, which have already been collected in previous studies.
Doel van het onderzoek
The hypotheses of the study is that TARC levels in patients with fever, other causes of lymphadenopathy and non-Hodgkin lymphoma will be significantly lower compared to patients with Hodgkin lymphoma.
Onderzoeksopzet
at entry
Onderzoeksproduct en/of interventie
ICF, venapunction once 10ml
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
In order to be eligible to participate in this study, a subject must meet all of the following criteria: - Age ¡Ý 18 years; - Ability to give written informed consent; And one of the following: (1) Lymph node enlargement of unknown cause for whicha diagnostic fine needle aspiration will be performedor (2) Presenting with fever at the emergency department or (3) Presenting with newly diagnosed or relapsed nodular lymphocyte predominant or non-Hodgkin lymphoma.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from participation in this study (applicable to all subgroups): - Ineligibility to give written informed consent; - Patients with active atopic disease or hepatic failure; - Patients already diagnosed with Hodgkin lymphoma
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6808 |
| NTR-old | NTR6994 |
| Ander register | : |