This study will investigate whether 24 hour dopamine infusion reduces the need of hospital admission for patients with exacerbation heart failure.
ID
Bron
Verkorte titel
Aandoening
Heart failure, home treatment, NYHA 3-4
Hartfalen, thuisbehandeling, NYHA 3-4
Ondersteuning
Groot wezenland 20
8011 JW Zwolle
The Netherlands
Groot wezenland 20
8011 JW Zwolle
The Netherlands
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Unplanned hospital admission for Heart Failure.
Achtergrond van het onderzoek
This study will investigate if 24 hours of Dopamine infusion 2 µg/kg/min at home situation, on top of standard treatment, can increase successful home treatments.
In patients presenting in hospital with exacerbation of heart failure (NYHA III-IV) that are candidate for home treatment.
Doel van het onderzoek
This study will investigate whether 24 hour dopamine infusion reduces the need of hospital admission for patients with exacerbation heart failure.
Onderzoeksopzet
1. Baseline;
2. Start treatment;
3. 24 hr after start treatment;
4. End home treatment;
5. 30 days follow-up.
Onderzoeksproduct en/of interventie
In this trial patients will be included that don't need to be hospitalized for the decompensated heart failure but can be recompensated with additional diuretics intra venous at home setting. The home treatment will be accompanied by the specialized nurses of the Chance@home team of the Isala klinieken. The patients that are randomized to Dopamine will receive 24 hours Dopamine on top of the standard treatment.
Publiek
Dokter Stolteweg 96
J. Klijn
Dokter Stolteweg 96
Zwolle 8025 AZ
The Netherlands
+31 (0)38 4262997
j.klijn@diagram-zwolle.nl
Wetenschappelijk
Dokter Stolteweg 96
J. Klijn
Dokter Stolteweg 96
Zwolle 8025 AZ
The Netherlands
+31 (0)38 4262997
j.klijn@diagram-zwolle.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Males or females ≥ 18 years of age;
2. Heart failure with NYHA class III-IV.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Cardiogenic shock;
2. Tachycardia, heart rate > 100 bpm;
3. Indication for hospitalization;
4. Severe aortic valve stenosis;
5. Severe hepatic or renal disease;
6. Patients with acute coronary syndromes;
7. Previous participation in the study;
8. Life expectancy of < 1 year;
9. Absolute contra indication for the use of Dopamine;
10. Women of child-bearing potential;
11. Unable to provide informed consent.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
Register | ID |
---|---|
NTR-new | NL2863 |
NTR-old | NTR3006 |
Ander register | METC / CCMO : 2011-002236-92 / NL36932.075.11; |
ISRCTN | ISRCTN wordt niet meer aangevraagd. |