Diabetes intervention study in Hindustani Surinamese

Background
Type 2 diabetes mellitus (DM) is highly prevalent among the Hindustani Surinamese; 30% in the group 45-60 years. This group is not only younger at presentation, but also at high risk of developing CVD. Early detection and treatment of DM may decrease the risk of complications. The objective of this study is to develop a screening program and lifestyle intervention for Hindustani Surinamese, aimed at identifying pre-diabetes and preventing DM.
Methods
Screening: 1500 Hindustani Surinamese in The Hague, aged 18 to 60 years, will be randomized to a standard or intensive recruitment strategy. Participants will be asked to donate a fasting blood sample and an oral glucose tolerance test will be carried out.
Intervention: Persons found to have impaired fasting glucose (fasting plasma glucose 5.6-< 7.0mmol/l) or impaired glucose tolerance (2-hour post-load glucose ¡Ý7.8-<11.1mmol/l) will be invited to participate in the intervention; they will be randomized to the lifestyle intervention or control group.
The content of the intervention is based on previous lifestyle interventions and will be targeted to the Hindustani Surinamese. Data on physical activity and dietary habits in the Hindustani Surinamese population are available from the SUNSET-study. A process evaluation among Surinamese participants in a physical exercise programme will provide insight into determinants of physical activity. Additional focus group discussions will take place among Hindustani Surinamese to gain further insight in determinants of physical activity and healthy dietary habits.
Results
The full design of the screening will be presented. Moreover, we will discuss the content of the the lifestyle intervention, including the results of the SUNSET data and the focus group discussions.
Conclusion
If the screening and lifestyle intervention are found to be feasible, a larger intervention study will be set up in order to determine the effectiveness of the screening followed by the intervention.

A systematic screening and a lifestyle-intervention for pre-diabetes targeted at the Hindustani Surinamese population will prevent or postpone the onset of diabetes mellitus type 2.

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Lifestyle intervention, which consists of dietary counseling and supervised physical activity.