Are CBT and IPT following initial treatment effective interventions that prevent relapse of recurrence of depression in the long-term? What are the mechanisms of change in CBT and IPT?
ID
Bron
Verkorte titel
Aandoening
cognitive behaviour therapy (CBT), n=75
interpersonal therapy (IPT), n=75
8-week waiting list, n=30
Ondersteuning
Academic Riagg Maastricht
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Depressive relapse/recurrence in the course of 24 months.
Achtergrond van het onderzoek
Although psychotherapy and antidepressants seem to help initially, many depressed patients suffer from relapse and recurrence. Recent findings suggest cognitive behaviour therapy (CBT) may reduce that risk in the long-term, but the mechanisms of change that prevent relapse and recurrence are still unknown. We will be the first to study the effectiveness of CBT compared to interpersonal therapy (IPT) for residual depression after initial treatment (reduction of symptoms; prevention of relapse and recurrence) and the underlying mechanisms of change (explicit and implicit measures). Participants will partly be recruited from an ongoing treatment study in primary care. These patients with residual depression will be offered psychotherapy (CBT or IPT) at our clinical site.
Doel van het onderzoek
Are CBT and IPT following initial treatment effective interventions that prevent relapse of recurrence of depression in the long-term? What are the mechanisms of change in CBT and IPT?
Onderzoeksproduct en/of interventie
Cognitive behaviour therapy (CBT), N=75;
Interpersonal therapy (IPT), N=75
8-week waiting list, N=30.
CBT= max. 20 sessions
IPT= max. 20 sessions
All interventions are delivered by qualified therapists under supervision at the Academic Riagg Maastricht.
Publiek
Lotte Lemmens
Maastricht University, Faculty of Psychology and Neuroscience, Department of Clinical Psychological Science
Maastricht 6200 MD
The Netherlands
+31 (0)43 3881874
Lotte.Lemmens@maastrichtuniversity.nl
Wetenschappelijk
Lotte Lemmens
Maastricht University, Faculty of Psychology and Neuroscience, Department of Clinical Psychological Science
Maastricht 6200 MD
The Netherlands
+31 (0)43 3881874
Lotte.Lemmens@maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. One or more episodes of MDD in past two years;
2. Initial treatment for depressive symptoms;
3. Residual symptoms of depression (BDI>=10).
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Chronic depression;
2. Concurrent treatment for depression;
3. Severe co-morbidity;
4. Medical conditions that explain depressive symptoms.
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL825 |
| NTR-old | NTR838 |
| Ander register | : N/A |
| ISRCTN | ISRCTN67561918 |