The cold fenotype of CRPS1 is associated with a better respons to percutaneous sympathetic blockade as opposed to the warm type of CRPS1.
ID
Bron
Verkorte titel
Aandoening
Complex regional pain syndrome type 1 (CRPS-1)
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Pain relief in the first week after blockade as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain.
Achtergrond van het onderzoek
Predictors of pain relief in sympathetic blockade for patients with CRPS-1 will be determined by a standardized evaluation of signs and symptoms in CRPS-1 patiënts with special attention to the existence of a warm or cold fenotype and measurements of skin temperature by means of infrared thermometry.
Doel van het onderzoek
The cold fenotype of CRPS1 is associated with a better respons to percutaneous sympathetic blockade as opposed to the warm type of CRPS1.
Onderzoeksproduct en/of interventie
Upper extremity CRPS-1: percutaneous blockade of Stellate ganglion at C7 with one single injection of bupivacaïne 0,25%
Lower extremity CRPS-1: percutaneous blockade of lumbar sympathetic chain at L3 with a single injection of bupivacaïne 0,25%.
Publiek
P.O. Box 5800
J. Geurts
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3877673
Jgeurt@sane.azm.nl
Wetenschappelijk
P.O. Box 5800
J. Geurts
Maastricht 6202 AZ
The Netherlands
+31 (0)43 3877673
Jgeurt@sane.azm.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Adult (18 years or more) male or female patiënts with CRPS1 as diagnosed by IASP criteria, with a duration of 12 months or less with moderate to severe pain (mean NRS of more than 4 in the previous week as measured 3 times daily in a pain diary with 0=no pain and 10= worst imaginable pain) and one extremity involved.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Patiënts of less than 18 years of age;
2. The existence of significant impairment of blood coagulation or the use of oral anticoagulant medication;
3. Patients suffering from diabetic polyneuropathia;
4. Patients who are unlikely to comply with study requirements;
5. Pregnant women;
6. CRPS1 with a duration of more than 12 months.
Opzet
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL595 |
| NTR-old | NTR651 |
| Ander register | : Ministry of economic affairs, number BSIK03016 |
| ISRCTN | ISRCTN71968956 |