Test the hypothesis that a divisional calculation of heat loss, and incorporation of skin temperature of the extremities during mild cold exposure will indicate an age effect on heat loss between young and elderly. An additional purpose is to test…
ID
Bron
Verkorte titel
Aandoening
Age, thermoregulation, skin blood flow, temperature, hysteresis
Ondersteuning
Universiteitssingel 50,
6229ER Maastricht,
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. Heat loss (W);<br>
2. Heat content (J/m^3).
Achtergrond van het onderzoek
In general elderly are predisposed to risk of both hypothermia and hyperthermia, even at mild cold or
heat exposure. Studies aimed at age related changes in mechanisms of thermoregulation to explain the
increased risk of elderly failed to observe differences in heat loss between young and elderly. This might be caused by a lumped approach of calculation of heat loss through mean skin temperature without
incorporation of temperatures of the extremities.
Doel van het onderzoek
Test the hypothesis that a divisional calculation of heat loss, and incorporation of skin temperature of the extremities during mild cold exposure will indicate an age effect on heat loss between young and elderly. An additional purpose is to test whether age effects on hysteresis are observable between cooling and warming subjects.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Subjects subjected to a mild cold (airtemperature 20C) and mild heat exposure (airtemperature 35C).
Publiek
Boris Kingma
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Wetenschappelijk
Boris Kingma
Universiteitssingel 50
Maastricht 6229 ER
The Netherlands
+31 43 388 4260,
b.kingma@hb.unimaas.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Caucasian healthy male;
2. Age between 18 to 28 years or age between 68 to 78 years;
3. 20 kg/m2 < BMI < 25 kg/m2;
4. 15% < Fat percentage < 20%;
5. 1.8 m2 < Dubois skin area < 2.0 m2;
6. 80mmHg < Mean arterial pressure < 90mmHg (rest, supine position).
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Female;
2. History of cardiovascular disease;
3. Carrier of electrically-sensitive implanted devices;
4. Deviant core temperature at day of experiment;
5. General feeling of illness at day of experiment.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1892 |
| NTR-old | NTR2007 |
| Ander register | MEC Maastricht University : 09-3-049 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |