Liposoluble vitamins in patients receiving longterm treatment with octreotide.

This is a cross-sectional explorative cohort study in patients receiving long-term octreotide treatment (longer than 18 months) for acromegaly or a carcinoid tumour. Patients will be investigated for vitamin-status at one time point. With this study we hope to get insight into the frequency and severity of deficiency of liposoluble vitamins in patients receiving long-term octreotide therapy. This will contribute to the early recognition and suppletion of (sub)clinical deficiencies thus improving patient’s health.


Single-center studie in Groningen, the Netherlands

There is some evidence pointing towards a risk liposoluble vitamin deficiency in patients receiving long-term octreotide treatment. This is becoming clear only recently as there are now patients using this drug since it became available. Groups especially using octreotide are acormegaly patients and patients with carcinoid, who have as additional reason for vitamin deficiency the fact that often a part of the small bowel is resected. However, vitamin status is not routinely assessed in these patients, even though vitamin deficiency can seriously affect quality of life.

This investigation will be done by blood analysis at one time point.

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