COMPAS studie

Rationale: Although hyperglycaemia in patients with diabetes mellitus (DM) is associated with complications after surgery, the frequency of glucose measurements in the perioperative period (during and after surgery) is notoriously low. In the general surgical population with DM, a postoperative glucose reduction of 1 mmol/l significantly decreases the occurrence of postoperative complications, implicating the necessity of glucose monitoring in the perioperative period. Over the past decade, several continuous glucose monitors (CGM) have been tested in the perioperative phase, but none has been deemed accurate enough without the need for placing a central venous line.

If we can accurately monitor glucose continuously during the perioperative period, this might improve glycaemic control, and thereby possibly reduce postoperative complications. Our objectives are to evaluate whether CGM improves glycaemic control.

Objective:

1. Does CGM improve glycaemic control in the perioperative period?

continuous glucose monitoring in the perioperative period improves glycaemic control in patients with diabetes

trial starts day of surgery

end of sensor period: three days after surgery

assessment of postoperative complications: 30 days after surgery

use of continuous glucose sensor in the perioperative period