ID
Bron
Verkorte titel
Aandoening
geheugen/ memory
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The main endpoints for the cognitive tasks are the behavioral score on the immediate and delayed recall of the VLT. This includes the number of words recalled immediately and after a 20 minute delay.
Onderzoeksproduct en/of interventie
Subjects will participate in 3 treatment conditions: i.e. placebo, biperiden 2 mg and 4 mg. All medications will be administered orally. Order of treatments will be balanced over three test sessions, which will be separated by a washout period of at least 7 days.
Publiek
Faculty of Psychology Dept. of Neuropsychology and Psychopharmacology
Laura Borghans
PO Box 616
Maastricht 6200 MD
The Netherlands
0031-(0)43-3881530
lgjm.borghans@maastrichtuniversity.nl
Wetenschappelijk
Faculty of Psychology Dept. of Neuropsychology and Psychopharmacology
Laura Borghans
PO Box 616
Maastricht 6200 MD
The Netherlands
0031-(0)43-3881530
lgjm.borghans@maastrichtuniversity.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
• In the opinion of the investigator, the participant is capable of understanding and complying with protocol requirements.
• The participant has a body mass index of 18.5-30 kg/m2, inclusive, at medical screening.
• The participant is aged 18 to 35 years, inclusive, at the time of informed consent.
• The volunteer is healthy, i.e. absence of all exclusion criteria and had normal or corrected to normal static binocular acuity with or without correction.
• The participant signs and dates a written informed consent form before the start of the experiments.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
• The subject has uncontrolled, clinically significant neurologic, cardiovascular, pulmonary, hepatic, renal, metabolic, gastrointestinal, or endocrine disease or other abnormality which may impact the ability of the subject to participate or potentially confound the study results.
• The volunteer has uncontrolled existing major psychiatric symptoms.
• The participant has known hypersensitivity to any component of the formulation or biperiden or related compounds.
• The subject has a history of drug abuse (defined as any illicit drug use) or a history of alcohol abuse within 1 year prior to the first visit or is unwilling to agree to abstain from alcohol from 24 hours prior to each test day and/or drugs throughout the study.
• The participant has any sensory or motor deficits which could reasonably be expected to affect test performance.
• Other exclusion criteria are smoking, excessive drinking (>20 glasses of alcohol containing beverages a week), pregnancy or lactation, use of medication other than oral contraceptives.
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL6094 |
NTR-old | NTR6241 |
Ander register | METC azM/UM : 163037 |